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388 stories matching this filter · ← front page

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  • A year after Vertex’s big launch, pain drug research faces a pivotal moment
    <p>Journavx revived an area of development long considered a graveyard. Can any other pain drugs keep investor excitement going?</p>
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Real-World Data Highlight Survival Benefit of Rituximab Maintenance After Frontline BR in MCL]]>
    <![CDATA[Rituximab following first-line bendamustine demonstrated significant OS and EFS real-world benefits in mantle cell lymphoma.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Dr Silbermann on Clinical Trial Design Considerations in Multiple Myeloma]]>
    <![CDATA[Rebecca Silbermann, MD, MMS, outlines key trial design considerations in multiple myeloma, including supportive care measures and end point selection.]]>
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onclive · 2mo ago
↗ source
  • <![CDATA[Retrospective Data Show Potential Real-World TTNT and OS Improvements With Next-Generation BTK Inhibitors in R/R MCL]]>
    <![CDATA[Retrospective data showed zanubrutinib was associated with improved real-world overall survival vs ibrutinib in second- or third-line mantle cell lymphoma.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[MimiVax and Roswell Park Open Phase 2 Trial of SurVaxM for Patients with Metastatic Neuroendocrine Tumors]]>
    <![CDATA[Roswell Park Comprehensive Cancer Center launched a phase 2 trial evaluating SurVaxM plus temozolomide in progressing neuroendocrine tumors.]]>
    onclive · 2mo ago↗ source
  • GSK cuts deal with Sino to broaden reach of hepatitis B drug
    <figure><div><img src="https://imgproxy.divecdn.com/mDk-h3NLB8udDPFuDlI7IPou1i9tJKJYucQXUnhK9vA/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0yMTc3MzEzMjc4LmpwZ…
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[INBRX-106 Plus Pembrolizumab Yields Efficacy Benefit vs Pembrolizumab Alone in First-Line HNSCC]]>
    <![CDATA[First-line INBRX-106 plus pembrolizumab generated a higher ORR vs pembrolizumab monotherapy in PD-L1–positive metastatic or unresectable HNSCC.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Treatment Intensification Gains Momentum in mCSPC Management]]>
    <![CDATA[During a recent OncLive Peer Exchange, prostate cancer experts discussed the evolving role of treatment intensification in mCSPC.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[FDA Approval of Brexu-Cel for R/R MCL Calls for Raised Awareness of CAR T-Cell Therapy Safety Considerations]]>
    <![CDATA[Luhua (Michael) Wang, MD, discusses the FDA approval of brexu-cel in mantle cell lymphoma and what to know about CAR T-cell therapy in clinical practice.]]>
    onclive · 2mo ago↗ source
  • Inhibrx delivers ‘differentiated’ cancer drug data; Fractyl starts diabetes gene therapy trial
    <figure><div><img src="https://imgproxy.divecdn.com/idsdMAHsPbXObDUtQW2qRG7uveBUVv6HCTn9NTtlDOI/g:nowe:0:0/c:1207:682/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0x…
    BioPharma Dive · 2mo ago↗ source
  • Biotech layoffs are easing, but is the worst over?
    <figure><div><img src="https://imgproxy.divecdn.com/TL3Qf7mHRlVjEhCJI35ocLIfavZ0TUEHiNIVNf4xjm8/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9TY3JlZW5zaG90XzIwMjYtMDUtMDdfYXRfM…
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Dr Randall on the Rationale for Investigating CSF-1R Inhibition in TGCT]]>
    <![CDATA[R. Lor Randall, MD, FACS discusses safety and efficacy data from the MANEUVER trial, which evaluated pimicotinib in TGCT.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Renal Cell Carcinoma: Real-World Factors in First-Line Treatment Selection]]>
    <![CDATA[In this segment, Dr. Elizabeth Plimack and Dr. Yasser Ged discuss how real-world patient factors influence first-line treatment decisions in renal cell carcinoma. ]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Expanding ctDNA Applications to RCC and Germ Cell Tumors]]>
    <![CDATA[Experts explain how ctDNA tracking in metastatic cancer guides therapy tweaks, flags relapse early, and where it fails in brain/peritoneal disease.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[RAPNO Criteria and MRI Assessment in PLGG: Recommendations vs. Real-World Practice]]>
    <![CDATA[Learn how clinicians weigh symptoms, MRI changes and family goals to decide when a child’s tumor needs treatment—beyond simple size cutoffs.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[ctDNA in Metastatic Urothelial Carcinoma]]>
    <![CDATA[Experts explain how ctDNA tracking in metastatic cancer helps tailor immunotherapy, spot relapse early, and guide dose breaks—plus key limitations.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Institutional Perspectives on Treatment Thresholds in PLGG]]>
    <![CDATA[Experts weigh PLGG treatment choices, balancing chemo and MEK inhibitors, guided by vision decline, symptoms, tumor growth, and family logistics.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Renal Cell Carcinoma: Practical Treatment Selection Across Risk Groups]]>
    <![CDATA[In this segment, Dr. Elizabeth Plimack leads a discussion with Dr. Sundhar Ramalingam and Dr. Yasser Ged on how clinicians approach treatment selection in renal cell carcinoma across diffe…
    onclive · 2mo ago↗ source
  • Precision in motion: Decoding the critical operations behind the logistics of next-generation cell and gene therapies
    <p>The future of medicine is here. See how specialized logistics are saving lives with next-gen cell and gene therapies.</p>
    BioPharma Dive · 2mo ago↗ source
  • The capacity crunch in biopharma is a location problem
    <p>Cell and gene therapies aren’t limited by ideas—they’re limited by where they’re built. See how “ready-now” locations change the math on scaling.</p>
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Nivolumab Plus SOC Therapy Shows Encouraging Disease Control in Grade Group 5 Prostate Cancer]]>
    <![CDATA[The regimen produced a 2-year freedom from biochemical recurrence rate of 90.3% in grade group 5 prostate cancer.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Five Under 5: Top Oncology Videos for the Week of 5/3]]>
    <![CDATA[The top 5 OncLive TV videos of the week cover insights in ovarian cancer, classical Hodgkin lymphoma, pancreatic cancer, melanoma, and myelofibrosis.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[ADCs Reshape the Future of Lung Cancer Care: From Second-Line Therapy to Earlier Intervention]]>
    <![CDATA[Judy Wang, MD, discusses how ADCs are transforming NSCLC treatment with improved responses, biomarker-driven care, and CNS activity.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[The OncFive: Top Oncology Articles for the Week of 5/3]]>
    <![CDATA[The FDA clears zenocutuzumab in NRG1 fusion+ cholangiocarcinoma, accepts a taletrectinib NDA in ROS1+ NSCLC for review, and more.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Dr Randall on Long-Term Responses and Functional Benefits With Pimicotinib in TGCT]]>
    <![CDATA[R. Lor Randall, MD, FACS discusses safety and efficacy data from the MANEUVER trial, which evaluated pimicotinib in TGCT.]]>
    onclive · 2mo ago↗ source