Treatment Intensification Gains Momentum in mCSPC Management

Treatment Intensification in mCSPC: Key TakeawaysADT monotherapy is no longer sufficient for many patients with mCSPC; data from several phase 3 studies have demonstrated that intensification beyond ADT improves efficacy outcomes.Since no head-to-head comparisons between ARPIs in randomized clinical trials are available, ARPI selection must be individualized.Real-world evidence should be used to supplement clinical trial data in treatment selection decision making.