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BioPharma Dive·4h ago·1 min read
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Cytokinetics reports Phase 3 success for Myqorzo but shares tumble as investors weigh market impact

Aug 31, 2026·read at BioPharma Dive ↗Positive readoutNeutral

At the European Society of Cardiology meeting, Cytokinetics presented Phase 3 data for Myqorzo in non‑obstructive hypertrophic cardiomyopathy, showing benefit in both forms of the disease and distinguishing it from Bristol Myers Squibb’s Camzyos.

The results were published in the New England Journal of Medicine and highlighted by analysts as a strong validation of the drug’s potential, yet the company’s stock fell sharply after the presentation.

Arrowhead Pharmaceuticals used the forum to stress its competitive edge, while a separate failed study from Alnylam added pressure on that firm’s heart‑failure program.

Investors are watching how the positive readout for Myqorzo translates into market share and pricing, as the sell‑off suggests caution despite the clinical win.

source

This writeup was produced by pharmadog from original reporting by BioPharma Dive.

Original headline: “ESC ‘26: Cytokinetics’ sell-off, Arrowhead’s edge and a heart drug autopsy”

read at BioPharma Dive ↗
1,188 words · retrieved 3h ago
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companies & drugs in this story

companies
CYTOKINETICS10ASTRAZENECA4BRISTOL2BRISTOL MYERS SQUIBB2BRISTOL MYERS SQUIBB CO2LEADING2IONIS PHARMACEUTICALS INCPFIZERUltragenyx Pharmaceutical Inc.
drugs
MYQORZO12aficamten12acoramidis hydrochloride5vutrisiran4nucresiran3olezarsen sodium3tafamidis3mavacamten2HypertriglyceridemiaOXYGENRare Disease
topics
Cardiology15Approval3Hepatology3Antisense Oligonucleotide (ASO)Heart FailureHematologyRare Disease

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