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  1. pharmadog
  2. ›drugs
  3. ›Tryngolza
drug · oligonucleotide
save

olezarsen sodium

Marketedupdated 3mo ago
by $IONS IONIS PHARMACEUTICALS INC🔗 ChEMBL
Approved
community read0 votes

Oligonucleotide drug with a maximum clinical stage of Unknown (across all indications), with 2 investigational indications.

all catalysts(0)

nothing on the calendar yet

Patent cliff

source: FDA Orange Book
first barrier falls
Dec 19, 2031
~5.4 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (6)

  • May 1, 2034method-of-use (U-4050)US 12509684
  • May 1, 2034compositionUS 9127276
  • May 1, 2034compositionUS 9163239
  • May 1, 2034compositionUS 9181549
  • Feb 14, 2034method-of-use (U-4050)US 9593333
  • Apr 27, 2032method-of-use (U-4050)US 9157082

FDA exclusivities (1)

  • Dec 19, 2031ODE-515Orphan Drug (7y)

News(5)

  • BioNTech picks Sobi CEO Oelkers to lead as founders plot new mRNA biotech
    BioNTech’s leadership transition was announced earlier this year, with CEO Ugur Sahin and CMO Özlem Türeci leaving to start a new mRNA company. Guido Oelkers of Swedish Orphan Biovitrum AB will tak…
    biospace · 8d ago
  • Biotechs bring big launches and pharma rivalries into Q2 earnings period
    With the second quarter earnings period underway, BioSpace examines five biotechs with meaningful catalysts that analysts and investors are watching.
    biospace · 14d ago
  • FDA panel confronting peptide controversy
    Today's biotech news features the FDA weighing the fate of peptides; approvals for RevMed, GSK; and data on Lilly's "triple-G."
    stat · 19d ago
  • Arrowhead hits ‘best-case scenario’ with latest results for fat-lowering drug
    To analysts, the drug’s apparent safety and effects on both triglyceride levels and pancreatitis cases should make it competitive with a rival Ionis therapy.
    biopharma_dive · 20d ago
  • Arrowhead puts pressure on Ionis with positive data for triglyceride lowering drug
    With Phase 3 data showing what analysts called a “potentially best-in-class profile,” Arrowhead Pharmaceuticals plans to submit for FDA approval of plozasiran by the end of the year—hoping to follo…
    biospace · 20d ago
brand
Tryngolza
trade names
Tryngolza
generic
olezarsen sodium
indication
Hypertriglyceridemia
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 21m ago
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