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  1. pharmadog
  2. ›drugs
  3. ›Attruby
drug
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acoramidis hydrochloride

Marketedupdated 5mo ago
by $BBIO BridgeBio Pharma, Inc.
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Patent cliff

source: FDA Orange Book
first barrier falls
Nov 22, 2029
~3.1 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (13)

  • Aug 16, 2039formulationUS 11260047
  • Aug 16, 2039formulationUS 12005043
  • Aug 16, 2039formulationUS 12539290
  • Mar 22, 2039method-of-use (U-4046)US 11058668
  • Mar 22, 2039method-of-use (U-4046)US 12070449
  • Feb 16, 2038compositionUS 10513497
  • Feb 16, 2038method-of-use (U-4046)US 11919865
  • May 5, 2031formulationUS 103986814.6y
  • May 5, 2031method-of-use (U-4046)US 108427774.6y
  • May 5, 2031formulationUS 88777954.6y
  • May 5, 2031formulationUS 91692144.6y
  • May 5, 2031compositionUS 96428384.6y
  • May 5, 2031method-of-use (U-4046)US 99138264.6y

FDA exclusivities (2)

  • Nov 22, 2031ODE-506Orphan Drug (7y)
  • Nov 22, 2029NCENew Chemical Entity (5y)3.1y

News(10)

  • 5 biotechs braving the commercial waters with product launches
    A growing number of biotechs are entering the market with newly launched medicines, a pattern indicative of “improving capital markets,” according to Jefferies’ Andrew Tsai.
    biospace · 17d ago
  • Mid-cap biotechs join Trump’s latest round of drug pricing deals
    Focused on Medicaid, the new pacts now involve more than just large pharmaceutical companies, but still aren’t expected to meaningfully impact drugmaker profits.
    biopharma_dive · 1mo ago
  • ESC ‘26: Cytokinetics’ sell-off, Arrowhead’s edge and a heart drug autopsy
    At a big meeting for cardiovascular medicines, Cytokinetics and Arrowhead aimed to separate their drugs from competitors while a failed study pressured Alnylam.
    biopharma_dive · 1mo ago
  • ‘Worse than expected’ Wainua data muddies water for TTR silencers
    AstraZeneca and Ionis Pharmaceuticals’ data drop divulging more details from its highly watched Phase 3 transthyretin silencer trial “further confuses the picture” for Wainua when combined with the…
    biospace · 1mo ago
  • AstraZeneca, Ionis data spark debate about RNA drugs’ impact on deadly heart disease
    Results published in NEJM raised questions about the benefits “silencer” medications provide on top of standard therapies for TTR cardiomyopathy and amplified investor pressure on Alnylam.
    biopharma_dive · 1mo ago
  • BridgeBio continues ATTR ascent as Alnylam’s Amvuttra falls short of expectations
    BridgeBio Pharma’s transthyretin amyloidosis medicine Attruby is off to a strong launch, while Alnylam lowered full-year sales guidance for competitor Amvuttra.
    biospace · 1mo ago
  • 5 companies advancing ATTR assets in the wake of Wainua’s fail
    The Phase 3 failure of AstraZeneca and Ionis Pharmaceuticals’ antisense therapy in transthyretin amyloid cardiomyopathy last month left the space reeling—and readjusting. BioSpace looks at five con…
    biospace · 2mo ago
  • Alnylam plunges as earnings deliver ‘one-two punch’
    The RNA-focused biotech shed 30% of its market value — or close to $12 billion — amid growing investor concerns about its main drug business.
    biopharma_dive · 2mo ago
  • Biotechs bring big launches and pharma rivalries into Q2 earnings period
    With the second quarter earnings period underway, BioSpace examines five biotechs with meaningful catalysts that analysts and investors are watching.
    biospace · 2mo ago
  • Pfizer deals extend patent life for a top-selling rare disease drug
    Settlements delaying the arrival of generic versions of tafamidis will protect billions in Pfizer revenue and have implications for others, including BridgeBio Pharma and Alnylam.
    biopharma_dive · 5mo ago
view all news mentions →
brand
Attruby
generic
acoramidis hydrochloride
indication
Familial Amyloid Cardiomyopathy
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 3h ago
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