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  1. pharmadog
  2. ›drugs
  3. ›Vyndamax
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tafamidis

Marketedupdated 3mo ago
by $PFE PFIZER INC
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Trials studying tafamidis

  • —A Retrospective Observational Study of Epidemiology and Outcomes in Transthyretin Amyloid Cardiomyopathy in Germanyrecruitingn=1
  • phase1A Study to Compare the Amount of Two Forms of Tafamidis in the Blood of Healthy Adults Under Fed Conditionsrecruitingn=24
  • —Korean Post-marketing Surveillance Vyndamax® Capsules for the Treatment of Transthyretin Amyloid Cardiomyopathyactive not recruitingn=110
  • —Real-World Effectiveness of High-Dose Tafamidis on Neurologic Disease Progression in Mixed-Phenotype Transthyretin Amyloid Cardiomyopathycompletedn=50
  • —A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)completedn=13
  • —A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in Indiacompletedn=6
  • phase4To Evaluate the Efficacy and Safety of Tafamidis Meglumine Soft Capsules in the Treatment of Adult Patients With Transthyretin Amyloid Polyneuropathyrecruitingn=15
  • phase1A Study to Compare Two Forms of Study Medicine Tafamidis in the Blood in Healthy Adultscompletedn=22
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
Dec 19, 2026
128 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (3)

  • Aug 31, 2035compositionUS 9770441
  • Dec 19, 2026compositionUS 7214695128d
  • Dec 19, 2026method-of-use (U-2524)US 7214696128d

FDA exclusivities (1)

  • May 3, 2026ODE-237Orphan Drug (7y)

News(10)

  • BridgeBio continues ATTR ascent as Alnylam’s Amvuttra falls short of expectations
    BridgeBio Pharma’s transthyretin amyloidosis medicine Attruby is off to a strong launch, while Alnylam lowered full-year sales guidance for competitor Amvuttra.
    biospace · 4h ago
  • Earnings roundup: Gilead’s ‘uncertain’ future, Pfizer’s crossroads and Merck’s PCSK9 launch
    Some analysts see warning signs in crucial drug launches from Gilead and Merck, while an important trial readout could change Pfizer’s growth trajectory.
    biopharma_dive · 7d ago
  • Pfizer expands multibillion-dollar cost-cutting plan
    Hatched three years ago, the restructuring is now expected to deliver $1 billion in new cost reductions and save Pfizer another $1.5 billion by streamlining drug production.
    biopharma_dive · 7d ago
  • 5 companies advancing ATTR assets in the wake of Wainua’s fail
    The Phase 3 failure of AstraZeneca and Ionis Pharmaceuticals’ antisense therapy in transthyretin amyloid cardiomyopathy last month left the space reeling—and readjusting. BioSpace looks at five con…
    biospace · 9d ago
  • Alnylam plunges as earnings deliver ‘one-two punch’
    The RNA-focused biotech shed 30% of its market value — or close to $12 billion — amid growing investor concerns about its main drug business.
    biopharma_dive · 12d ago
  • Biotechs bring big launches and pharma rivalries into Q2 earnings period
    With the second quarter earnings period underway, BioSpace examines five biotechs with meaningful catalysts that analysts and investors are watching.
    biospace · 14d ago
  • Royalty Pharma pens $425M deal for slice of sales on AstraZeneca’s ATTR drug
    Royalty Pharma has secured a stake in another transthyretin-mediated amyloidosis drug, this time paying $125 million upfront to Neurimmune for a cut of the sales of its AstraZeneca-partnered med.
    fiercebiotech · 21d ago
  • AstraZeneca, Ionis drug fails big heart disease study in major setback
    Eplontersen’s failure in transthyretin-mediated amyloidosis cardiomyopathy caught Wall Street analysts by surprise and boosted the outlook of rival drugs from Alnylam and BridgeBio Pharma.
    biopharma_dive · 1mo ago
  • 10 clinical trials to watch in the second half of 2026
    The biotechnology sector’s upswing accelerated in the first half. Positive results from anticipated trials in lung cancer, Alzheimer’s and multiple autoimmune conditions could add to the momentum.
    biopharma_dive · 1mo ago
  • STAT+: Pharmalittle: We’re reading about the FDA speeding up trials, a Supreme Court hearing on ‘skinny labels,’ and more
    The FDA announced efforts to make clinical trials more efficient, starting by reviewing data in real time from trials conducted by AstraZeneca and Amgen
    stat · 3mo ago
view all news mentions →
brand
Vyndamax
generic
tafamidis
indication
Familial Amyloid Cardiomyopathy
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 21m ago
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