drug
mavacamten
Marketedupdated 5mo agoby Bristol-Myers Squibb Co
Approvedcommunity read0 votes
all catalysts(0)
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Trials studying mavacamten
- —A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US
- —A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- —A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China
- —COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)
- —Effectiveness and Treatment Patterns of Mavacamten in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan (MANAGE-HCM)
- phase4A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)
- phase3A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCM
- —Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan
Patent cliff
source: FDA Orange Bookfirst barrier falls
Apr 28, 2027
206 days
Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.
patents (8)
- Apr 28, 2036compositionUS RE50050
- Apr 28, 2036compositionUS RE50050
- Apr 28, 2036compositionUS RE50050
- Apr 28, 2036compositionUS RE50050
- Jun 19, 2034method-of-use (U-3373)US 9585883
- Jun 19, 2034method-of-use (U-3373)US 9585883
- Jun 19, 2034method-of-use (U-3373)US 9585883
- Jun 19, 2034method-of-use (U-3373)US 9585883
FDA exclusivities (12)
- Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
- Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
- Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
- Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
- Apr 28, 2027NCENew Chemical Entity (5y)206d
- Apr 28, 2027NCENew Chemical Entity (5y)206d
- Apr 28, 2027NCENew Chemical Entity (5y)206d
- Apr 28, 2027NCENew Chemical Entity (5y)206d
- Jun 15, 2026M-297Method (3y)
- Jun 15, 2026M-297Method (3y)
- Jun 15, 2026M-297Method (3y)
- Jun 15, 2026M-297Method (3y)
News(10)
- United Therapeutics' legal victory; BMS' Camzyos approved for kidsPlus, news about United Therapeutics, MindRank, Novo, Atara Biotherapeutics, Pierre Fabre, Monte Rosa Therapeutics, Bristol Myers Squibb’s Camzyos and Skopos Bio. Nektar Therapeutics' shares drop 2…endpoints · 2d ago
- Stripped of AstraZeneca safety net, BMS could face ‘carnage’ if high-risk clinical trial failsBMS is barreling toward a clinical trial readout that an H.C. Wainwright analyst believes could contribute to the return of mergers between mega-cap drugmakers.biospace · 1mo ago
- ESC ‘26: Cytokinetics’ sell-off, Arrowhead’s edge and a heart drug autopsyAt a big meeting for cardiovascular medicines, Cytokinetics and Arrowhead aimed to separate their drugs from competitors while a failed study pressured Alnylam.biopharma_dive · 1mo ago
- Capricor shares spike on CEO comments; Cytokinetics sues Bristol MyersThe FDA is “willing to review” an updated submission for Capricor’s Duchenne cell therapy, its CEO said. Elsewhere, a heart drug battle spilled into court and Rigel priced the first “Protac” medicine.biopharma_dive · 1mo ago
- Braveheart pumps more life into biotech IPO market with $382M expected debutBraveheart Bio has emerged on the Nasdaq with an upsized expected initial public offering—marking the public entrance of the twenty-second biotech this year.biospace · 1mo ago
- Braveheart charges past expectations with $382.5M IPO to fund cardio drug from HengruiBraveheart Bio has overcome its own IPO expectations, rallying $382.5 million in an upsized listing to fund its cardiovascular ambitions.fiercebiotech · 1mo ago
- Cardiac drug developer Braveheart banks more than $382M in IPOBraveheart is one of five biotechnology firms that made plans to price an IPO this week. They could collectively raise more than $1 billion from public investors.biopharma_dive · 1mo ago
- 5 NextGen winners who went public this year (and which ones are hiring)BioSpace NextGen honorees made up one-third of the U.S. biotechs that have publicly debuted in 2026. Most are looking for biopharma professionals to join their teams.biospace · 1mo ago
- An AstraZeneca-Bristol Myers megamerger? Wall Street isn’t thrilled.In fact, the former lost tens of billions of dollars in market value following reports of a potential tie-up between the pharmaceutical giants.biopharma_dive · 2mo ago
- Sanofi to ‘rebuild trust’ with Regeneron; Apnimed adds to string of ‘upsized’ biotech IPOsSanofi wants to broaden the company’s productive partnership with Regeneron, its CEOs said. Elsewhere, Bristol Myers delayed two anticipated study readouts and a Shionogi-backed startup went public.biopharma_dive · 2mo ago
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