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  1. pharmadog
  2. ›drugs
  3. ›Camzyos
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mavacamten

Marketedupdated 5mo ago
by Bristol-Myers Squibb Co
Approved
community read0 votes

all catalysts(0)

nothing on the calendar yet

Trials studying mavacamten

  • —A Study to Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the USactive not recruitingn=150
  • —A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)recruitingn=1,700
  • —A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in Chinarecruitingn=500
  • —COLLIGO-HCM: A Multinational Observational Study of the Real-World Effectiveness of Mavacamten Among Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM)active not recruitingn=331
  • —Effectiveness and Treatment Patterns of Mavacamten in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan (MANAGE-HCM)recruitingn=36
  • phase4A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)recruitingn=50
  • phase3A Long-Term Safety Extension Study of Mavacamten in Adults Who Have Completed MAVERICK-HCM or EXPLORER-HCMcompletedn=314
  • —Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japanrecruitingn=200

Patent cliff

source: FDA Orange Book
first barrier falls
Apr 28, 2027
206 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (8)

  • Apr 28, 2036compositionUS RE50050
  • Apr 28, 2036compositionUS RE50050
  • Apr 28, 2036compositionUS RE50050
  • Apr 28, 2036compositionUS RE50050
  • Jun 19, 2034method-of-use (U-3373)US 9585883
  • Jun 19, 2034method-of-use (U-3373)US 9585883
  • Jun 19, 2034method-of-use (U-3373)US 9585883
  • Jun 19, 2034method-of-use (U-3373)US 9585883

FDA exclusivities (12)

  • Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
  • Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
  • Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
  • Apr 28, 2029ODE-398Orphan Drug (7y)2.6y
  • Apr 28, 2027NCENew Chemical Entity (5y)206d
  • Apr 28, 2027NCENew Chemical Entity (5y)206d
  • Apr 28, 2027NCENew Chemical Entity (5y)206d
  • Apr 28, 2027NCENew Chemical Entity (5y)206d
  • Jun 15, 2026M-297Method (3y)
  • Jun 15, 2026M-297Method (3y)
  • Jun 15, 2026M-297Method (3y)
  • Jun 15, 2026M-297Method (3y)

News(10)

  • United Therapeutics' legal victory; BMS' Camzyos approved for kids
    Plus, news about United Therapeutics, MindRank, Novo, Atara Biotherapeutics, Pierre Fabre, Monte Rosa Therapeutics, Bristol Myers Squibb’s Camzyos and Skopos Bio. Nektar Therapeutics' shares drop 2…
    endpoints · 2d ago
  • Stripped of AstraZeneca safety net, BMS could face ‘carnage’ if high-risk clinical trial fails
    BMS is barreling toward a clinical trial readout that an H.C. Wainwright analyst believes could contribute to the return of mergers between mega-cap drugmakers.
    biospace · 1mo ago
  • ESC ‘26: Cytokinetics’ sell-off, Arrowhead’s edge and a heart drug autopsy
    At a big meeting for cardiovascular medicines, Cytokinetics and Arrowhead aimed to separate their drugs from competitors while a failed study pressured Alnylam.
    biopharma_dive · 1mo ago
  • Capricor shares spike on CEO comments; Cytokinetics sues Bristol Myers
    The FDA is “willing to review” an updated submission for Capricor’s Duchenne cell therapy, its CEO said. Elsewhere, a heart drug battle spilled into court and Rigel priced the first “Protac” medicine.
    biopharma_dive · 1mo ago
  • Braveheart pumps more life into biotech IPO market with $382M expected debut
    Braveheart Bio has emerged on the Nasdaq with an upsized expected initial public offering—marking the public entrance of the twenty-second biotech this year.
    biospace · 1mo ago
  • Braveheart charges past expectations with $382.5M IPO to fund cardio drug from Hengrui
    Braveheart Bio has overcome its own IPO expectations, rallying $382.5 million in an upsized listing to fund its cardiovascular ambitions.
    fiercebiotech · 1mo ago
  • Cardiac drug developer Braveheart banks more than $382M in IPO
    Braveheart is one of five biotechnology firms that made plans to price an IPO this week. They could collectively raise more than $1 billion from public investors.
    biopharma_dive · 1mo ago
  • 5 NextGen winners who went public this year (and which ones are hiring)
    BioSpace NextGen honorees made up one-third of the U.S. biotechs that have publicly debuted in 2026. Most are looking for biopharma professionals to join their teams.
    biospace · 1mo ago
  • An AstraZeneca-Bristol Myers megamerger? Wall Street isn’t thrilled.
    In fact, the former lost tens of billions of dollars in market value following reports of a potential tie-up between the pharmaceutical giants.
    biopharma_dive · 2mo ago
  • Sanofi to ‘rebuild trust’ with Regeneron; Apnimed adds to string of ‘upsized’ biotech IPOs
    Sanofi wants to broaden the company’s productive partnership with Regeneron, its CEOs said. Elsewhere, Bristol Myers delayed two anticipated study readouts and a Shionogi-backed startup went public.
    biopharma_dive · 2mo ago
view all news mentions →
brand
Camzyos
generic
mavacamten
indication
Hypertrophic Cardiomyopathy
phase
marketed
Data sources
ClinicalTrials.gov
last refreshed 44m ago
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