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425 stories matching this filter · ← front page

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  • <![CDATA[Dr Gruenbaum on Where Alternative Options to BTK Inhibitors Stand in MCL]]>
    <![CDATA[Lore Gruenbaum, PhD, discusses alternative treatments to BTK inhibitors like bispecific antibodies and CAR T-cell therapy in mantle cell lymphoma.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[The PYNNACLE Phase 2 trial assessing rezatapopt, a selective p53 reactivator, in patients with advanced or metastatic solid tumors harboring a TP53 Y220C mutation: Interim analysis of patients with ovarian cancer]]>
    <![CDATA[Alison Schram, MD, discusses interim PYNNACLE phase 2 data showing that single-agent rezatapopt produced clinically meaningful responses and a manageable safety profile in heavily pretreat…
    onclive · 2mo ago↗ source
  • <![CDATA[Characterization and Management of Sevabertinib induced Diarrhea in the SOHO 1 study ]]>
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Hematology6
Pulmonology5
Infectious Disease4
Ophthalmology3
Dermatology2
<![CDATA[This analysis from the SOHO-01 study evaluated the safety profile of sevabertinib in HER2-mutated non–small cell lung cancer, with a specific focus on treatment-related diarrhea. Diarrhea…
onclive · 2mo ago↗ source
  • <![CDATA[First-Line Danvatirsen Plus Pembrolizumab Fails to Improve Response Rates in Metastatic HNSCC]]>
    <![CDATA[Danvatirsen in combination with pembrolizumab did not result in an ORR improvement vs pembrolizumab alone in first-line recurrent/metastatic HNSCC.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Cumulative ADC Toxicities and Closing Reflections: Managing Edema, Fatigue, and Optimizing Long-Term Tolerability]]>
    <![CDATA[This concluding segment addresses cumulative toxicities affecting long-term antibody-drug conjugate tolerability, with Hope Rugo, MD and Aaron Lisberg, MD discussing edema, fatigue, and st…
    onclive · 2mo ago↗ source
  • Odyssey, on second try, snags $279M in an IPO
    <figure><div><img src="https://imgproxy.divecdn.com/szYDL8kkQd6XaSVgvjJPYl2j0snveijWs_0sZ-B522Y/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDYyODUzODA3LmpwZ…
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Dr Sznol on Optimal Treatment Sequencing in Melanoma]]>
    <![CDATA[Mario Sznol, MD, discusses the challenges of determining whether to recommend adjuvant therapy for patients with melanoma based on current data. ]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Mentorship Is Key to Advance the Next Generation of Oncology Researchers]]>
    <![CDATA[Theresa A. Guise, MD, FASBMR, and Stephanie S. Watowich, PhD, discuss their elections as AAAS fellows and offer guidance for early-career investigators. ]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Dr Mauro on the Significance of Alternative TKI Formulations in CML]]>
    <![CDATA[Michael Mauro, MD, details the FDA approval of the small-molecule formulation of dasatinib and other alternate TKI formulations in chronic myeloid leukemia.]]>
    onclive · 2mo ago↗ source
  • Sarepta tumbles as its gene therapy sales decline further
    <figure><div><img src="https://imgproxy.divecdn.com/XaTqfcte0RAZt6-RIcgWQ5i2KmL-mKKasPXR8xjfQW8/g:nowe:0:858/c:4256:2405/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9TYXJlcHRhX0Jvc…
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Women With Bladder Cancer Face Diagnostic Delays as Symptoms Mimic UTIs, Experts Warn]]>
    <![CDATA[Timothy N. Clinton, MD, and Stephanie A. Berg, DO, discuss gender differences in bladder cancer during Bladder Cancer Awareness Month.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Dr Olawaiye on the FDA Approval of Relacorilant Plus Nab-Paclitaxel in PROC]]>
    <![CDATA[Alexander B. Olawaiye, MD, discusses the clinical significance of the FDA approval of relacorilant plus nab-paclitaxel in PROC.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Daraxonrasib Monotherapy Elicits Meaningful Responses in Previously Treated, RAS-Mutated Pancreatic Cancer]]>
    <![CDATA[Phase 1/2 data showed an ORR of 35% with daraxonrasib in second-line RAS G12-mutated pancreatic ductal adenocarcinoma.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Sylvester Comprehensive Cancer Center Identifies a Screening Gap to Prevent a Type of Leukemia in the U.S.]]>
    <![CDATA[Researchers at Sylvester identified populations in the US where this cancer may be largely preventable by addressing mother‑to‑child transmission of the virus.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[FDA Completes Type A Meeting Following CRL for Tabelecleucel in EBV+ R/R Post-Transplant Lymphoproliferative Disease]]>
    <![CDATA[The FDA and Atara Biotherapeutics completed a Type A meeting to discuss the CRL for tabelecleucel in post-transplant lymphoproliferative disease.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[ASCO 2026 TNBC Deep Dive: Breast Cancer Experts Preview Practice-Informing Studies]]>
    <![CDATA[Experts spotlight the triple-negative breast cancer abstracts they’re most excited to see at the 2026 ASCO Annual Meeting. ]]>
    onclive · 2mo ago↗ source
  • Angelini to buy Catalyst in $4B play for rare neuro drugs
    <figure><div><img src="https://imgproxy.divecdn.com/4_eQ3BQP0sHe3AjR5s7bySznoaDhyqMpmhkmNubOdkU/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDQwMTY4MDMyXzEua…
    BioPharma Dive · 2mo ago↗ source
  • Entrada shares dive as Duchenne results disappoint
    <figure><div><img src="https://imgproxy.divecdn.com/xa_T0oT9Hj8F-wJjKfJeFkbn4Yqp_lT58dL0S4GszxY/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy02MjEzNjQ4MDJfMS5qc…
    BioPharma Dive · 2mo ago↗ source
  • Roche to acquire digital pathology firm PathAI in deal potentially worth over $1B
    <figure><div><img src="https://imgproxy.divecdn.com/Q9vt9_gxDkyyl1zgpo6ZBBNf6InJ95ZMxSRGRm4nTFk/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS8yQTROWEtOLmpwZw==.webp"/></div></f…
    BioPharma Dive · 2mo ago↗ source
  • <![CDATA[Track the Lung Cancer Abstracts That are Gaining Attention at ASCO 2026]]>
    <![CDATA[Read on to see what data are poised to shape clinical discussions and decision-making in lung cancer at 2026 ASCO Annual Meeting in Chicago, Illinois.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[EGFR-Targeted Therapy Sequencing After Resistance in NSCLC]]>
    <![CDATA[Learn how clinicians tackle EGFR lung cancer resistance—using NGS, radiation, chemo, amivantamab, and ADCs to tailor next-line therapy.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[HERIZON-GEA-01 Study Design, Geographic Distribution, and PD-L1 Testing Considerations]]>
    <![CDATA[Experts debate PD‑L1 testing in HER2+ metastatic gastric cancer as new trial data reshapes when to add immunotherapy.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Integrating Evidence and Identifying Future Research Needs in Metastatic Castration Sensitive Prostate Cancer (mCSPC)]]>
    <![CDATA[Experts debate real-world evidence for prostate cancer drug comparisons, weighing trial limits, bias, and data that guides care.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Approaching First-Line Treatment in PD-L1 CPS <1 HER2-Positive GEA]]>
    <![CDATA[Zanidatamab’s dual HER2 binding shows striking single-agent activity in gastric and biliary cancers, hinting at synergy beyond pertuzumab-trastuzumab blockade.]]>
    onclive · 2mo ago↗ source
  • <![CDATA[Co-Occurring Mutations in NSCLC: Influence on Prognosis and Immunotherapy Response]]>
    <![CDATA[Learn how STK11 and MTAP loss reshape NSCLC prognosis, immunotherapy response, and open doors to dual-checkpoint and PRMT5 inhibitor trials.]]>
    onclive · 2mo ago↗ source