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BioPharma Dive·Sep 11·1 min read
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Karyopharm Secures One-Month Debt Extension While Awaiting Xpovio Decision

Sep 11, 2026·read at BioPharma Dive ↗DealNeutral

Karyopharm Therapeutics, facing cash constraints, has negotiated a temporary reprieve on a $15.8 million debt that was due.

Under the agreement, lenders and noteholders will refrain from enforcement actions until mid-October, giving the company about a month to explore financing or strategic options. In return, Karyopharm will issue $20 million of newly created convertible stock as a fee.

The company is also awaiting a regulatory decision on its multiple myeloma drug Xpovio for a potential indication in myelofibrosis.

Analysts noted that while the extension is not a long-term solution, it provides needed breathing room.

The brief also mentioned Amgen’s interest in expanding the use of Imdelltra in combination with AstraZeneca’s Imfinz, but no further details were provided.

source

This writeup was produced by pharmadog from original reporting by BioPharma Dive.

Original headline: “Karyopharm pushes off debt payment; Amgen eyes broader Imdelltra use”

read at BioPharma Dive ↗
783 words · retrieved Sep 11
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companies & drugs in this story

companies
AMGEN7Karyopharm Therapeutics Inc.3ASTRAZENECA2Encoded Therapeutics Inc2Schrodinger, Inc.2Ajax Therapeutics IncBridgeBio Oncology Therapeutics, Inc.ELI LILLY COGILEADGILEAD SCIENCES INCLILLYUltragenyx Pharmaceutical Inc.
drugs
IMDELLTRA6tarlatamab6durvalumab3XPOVIO2selinexor2BBO-8520DUPIXENTETX-101Small Moleculesdupilumab
topics
Oncology9NSCLC4Atopic Dermatitis3Pulmonology3Approval2Gene Therapy (AAV)2Multiple Myeloma2Pain2Breast CancerDermatologyEpilepsyKRASNeurologyRare Disease

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