After tasting IPO success, Hemab’s CEO seeks ‘flavor of a multi-product coagulation company’

Now accepting nominations for the Fierce Innovation Awards - Submit your application today Biotech After tasting IPO success, Hemab’s CEO seeks ‘flavor of a multi-product coagulation company’ By Will Maddox Aug 13, 2026 9:00am Hemab Therapeutics biotech IPO Nasdaq Incyte Hemab’s Kendall Square office in Cambridge, Massachusetts gives visitors a rare view above the Charles River and downtown Boston. It’s an enviable backdrop for realizing the company’s vision of becoming the premier clotting biopharma. The view isn’t the only thing keeping spirits high at the newly public company, which completed an upsized $301.5 million IPO in May to fund its pipeline of therapies aimed at helping patients living with bleeding disorders.

As well as underwriters helping lift the final IPO proceeds to $346.7 million, the biotech's stock had tripled in value to $53.48 by August 12 from a May debut of $18. The company ended June with $457.5 million in the bank, which Hemab expects to pave a cash runway into 2029. The biopharma has modestly expanded its workforce since the IPO, and now employs 80 people.

With the post-IPO quiet period having come to an end, CEO Benny Sørensen, M.D., Ph.D., was free to sit down with Fierce to discuss Hemab’s future as a publicly listed company. Sørensen called the Nasdaq listing both a “natural step” and a “dream come true.” The IPO was a result of years of hard work and an expected part of the plan, but he was pleased with the scale of the response. The company, which has dual headquarters in Copenhagen, Denmark and Cambridge, has raised several rounds of funding over the years.

This included a $55 million series A in 2021, a $135 million series B in 2023 and a $157 million series C last year. “It was clear that to advance the company, build out the portfolio, and be serious about this mission of building the ultimate coagulation company, the natural next step was a public offering to access those capital markets,” Sørensen explained. Fortunate that the company’s data and progress lined up with a wide-open IPO window, Sørensen said he encountered excitement for Hemab’s vision and progress when the company set out on its roadshow.

“We had good interest from very high-quality investors,” he said. “Not just a few, but multiple—positioning us for building a book that is highly concentrated with top-notch investors. It felt like a dream come true.” Sørensen said Hemab had already achieved its initial goal of having five projects in development by 2025.

The company recently shared data on three of those programs, including its bispecific antibody sutacimig, which is in phase 2 studies for patients with the rare inherited bleeding disorders Glanzmann thrombasthenia (GT) and factor VII deficiency (FVIID). At the International Society on Thrombosis and Haemostasis Congress last month, the company unveiled phase 2 data from a long-term extension study of sutacimig in GT that it said demonstrated the therapy's “potential to shift people ... from reactive, IV-dependent treatment to subcutaneous prophylaxis.” Hemab is gearing up for a phase 3 trial later this year.

This summer also saw Hemab read out data for its phase 2-stage antibody HMB-002. The subcutaneous prophylactic injection targets the lifelong inherited bleeding disorder von Willebrand disease (VWD), and has been tied to a 2.4-fold or greater peak increase in von Willebrand factor, a glycoprotein that helps blood clot. “The hardworking may be allowed to be lucky too,” said Sørensen as he reflected on the findings.

“The HMB-002 data were much better than anyone had hoped for or thought they would be.” Last month, Hemab unveiled HMB-003, a non-hormonal direct plasmin inhibitor designed to reduce bleeding across multiple settings, beginning with heavy menstrual bleeding. The asset is set to enter the clinic later this year. The fatty acid-conjugated peptide resembles Wegovy or Mounjaro in its delivery platform, but is tailored for women with heavy menstrual bleeding, Sørensen said.

“Taboo and stigma hold on to this, and [heavy bleeding] generates iron deficiency and anemia,” the CEO explained. “On average, a woman with heavy menstrual bleeding is losing 3.6 weeks from work every year.” Sørensen emphasized the company’s commitment to women’s health, pointing out that Hemab has made an effort to ensure women are well represented in its trials. A total of 86% of the participants in the phase 1 study of HMB-001 were female, according to the biotech, with women accounting for half of the patients enrolled in the phase 2 trial for sutacimig in GT.

“There's a recognition that this is a completely underappreciated, unmet need,” Sørensen said. “It requires modern treatment options to empower women to control this.” Sørensen has dedicated much of his career to hematology and coagulation. Before joining Hemab as CEO in 2021, his previous roles included senior director of clinical research at Alnylam Pharmaceuticals, where he led development of Qfitlia and other hematology products, as well as global medical director at Baxter Healthcare, where he helped develop the hemophilia therapy Adynovate and the VWD drug Vonvendi, which were acquired by Takeda in the 2019 Shire buyout.

Before joining the biotech industry, he was the director of the haemostasis research unit and honorary lecturer at Guy’s and St. Thomas’ Hospital and King’s College London School of Medicine. Sørensen said two of Hemab's existing five pipeline programs have yet to be unveiled, and he already has his sights set on launching two commercial products, advancing two new late-stage programs and entering two other drugs into phase 1/2 by 2030.

This will give Hemab “the flavor of a multi-product coagulation company,” he explained. The CEO is hopeful about the future for patients living with bleeding disorders. Sørensen pointed to the success of Genentech’s clotting medicine, which transformed hemophilia “from being a debilitating disease to being put on Hemlibra today.” These medical advances mean “you are not going to die from hemophilia,” he pointed out.

Still, there is plenty of unmet need in the bleeding disorder space. “We left so many behind, and now we're on the mission of trying to close the gap,” Sørensen said. Hemab Therapeutics biotech IPO Nasdaq Incyte Takeda Biotech