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  1. pharmadog
  2. ›drugs
  3. ›Mounjaro
drug · protein
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tirzepatide

pre_registrationupdated 3mo ago
by Eli Lilly and Co🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 6
  • drugZEPBOUND112 co-mentions · 40 sources
  • drugMOUNJARO112 co-mentions · 40 sources
  • tagApproval96 co-mentions · 24 sources
  • companyEli Lilly and Co48 co-mentions · 24 sources
  • tagRecall16 co-mentions · 16 sources
  • drugcyanocobalamin2 co-mentions · 2 sources

Protein drug with a maximum clinical stage of Approval (across all indications), with 6 approved and 8 investigational indications.

targets

Glucagon-like peptide 1 receptorGastric inhibitory polypeptide receptor

all catalysts(0)

nothing on the calendar yet

Trials studying tirzepatide

  • phase2A Study to Evaluate ALN-2232 in Participants With Obesityrecruitingn=156
  • phase3A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)recruitingn=4,500
  • phase4AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetesnot yet recruitingn=285
  • phase3A Study of Tirzepatide in Adolescents With Obesity and Weight-Related Comorbidities (SURMOUNT-ADOLESCENTS-2)recruitingn=300
  • phase3A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin, SGLT2 Inhibitor or Bothactive not recruitingn=1,023
  • phase3Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweightrecruitingn=290
  • phase2A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidityactive not recruitingn=285
  • phase3Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Studyrecruitingn=350
more trials →

News(10)

  • Roche pours $750M into Oregon manufacturing plant as obesity push expands
    After committing $2 billion to a new North Carolina facility to boost capacity for its next-gen obesity candidates, Roche's Genentech is putting down more cash to expand a device fill-finish site i…
    biospace · 9h ago
  • Enveda’s exercise-simulating obesity tablet clears early clinical test
    Touting an “exceptional” gastrointestinal safety profile for its oral obesity drug candidate in a study of healthy volunteers, Enveda plans to test the asset in people stopping GLP-1 treatment.
    biospace · 1d ago
  • Novo takes first round of oral obesity duel. Can it stay ahead of Lilly?
    Despite coming away with an early victory over Eli Lilly in the oral obesity face-off, analysts don’t expect Novo Nordisk’s lead to last for very long.
    biospace · 2d ago
  • Amylyx eyes FDA filing for GLP-1 blocker after late-stage win in post-bariatric hypoglycemia
    With a Phase 3 trial showing a reduction of serious and severe hypoglycemic episodes in patients who have undergone weight loss surgery, Amylyx Pharmaceuticals plans to file for approval this year.…
    biospace · 2d ago
  • Amylyx readies approval push after GLP-1 inhibitor halves blood sugar crashes in ph. 3 win
    Amylyx Pharmaceuticals’ $35 million bet on the GLP-1 receptor antagonist avexitide appears to have paid off, with the molecule cutting the number of dangerous blood sugar crashes by more than half…
    fiercebiotech · 3d ago
  • STAT+: Pharmalittle: We’re reading about California insulin sales, a Moderna patent battle, and more
    Seven months after the launch of its own low-cost insulin brand, California has distributed more than 120,000 five-pen packs of insulin glargine priced at $55 each
    stat · 7d ago
  • After tasting IPO success, Hemab’s CEO seeks ‘flavor of a multi-product coagulation company’
    With the post-IPO quiet period having come to an end, CEO Benny Sørensen, M.D., Ph.D., was free to sit down with Fierce to map out Hemab’s future.
    fiercebiotech · 9d ago
  • Opinion: Burdensome Medicare GLP-1 program may keep patients from accessing $50 per month weight loss drugs
    Medicare’s new weight loss drug program “risks creating barriers at precisely the moment when confidence in broader GLP‑1 coverage is most needed,” writes Jeffrey Millstein.
    stat · 9d ago
  • Lilly, FDA retatrutide biologic dispute comes to a head as submission nears
    A legal dispute between the FDA and Eli Lilly over whether the highly anticipated obesity candidate retatrutide is indeed a biologic has come to a head as the company prepares to submit the medicin…
    biospace · 15d ago
  • Lilly climbs, Novo falls as obesity drug battle intensifies
    A research disappointment and a miss on Wegovy pill sales hurt Novo, while Lilly’s injectable franchise once again surpassed analyst expectations.
    biopharma_dive · 15d ago
view all news mentions →
brand
Mounjaro
trade names
Mounjaro, Mounjaro (autoinjector), Zepbound, Zepbound (autoinjector)
generic
tirzepatide
MOA
Glucagon-like peptide 1 receptor agonist; Gastric inhibitory polypeptide receptor agonist
indication
Cardiovascular Risk Factors
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 35m ago
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