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PUBLIC COMPANY
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$ALNYALNYLAM PHARMACEUTICALS, INC.

$ALNY229.30-5.49%
Cambridge, MA, USupdated 7h ago

Alnylam Pharmaceuticals, Inc. is an American biopharmaceutical company focused on the discovery, development and commercialization of RNA interference (RNAi) therapeutics for genetically defined diseases. The company was founded in 2002 and is headquartered in Cambridge, Massachusetts. In 2016, Forbes included the company on its "100 Most Innovative Growth Companies" list.

Website ↗SEC EDGAR ↗Yahoo Finance ↗
community read0 votes
pipeline
6
marketed
4
phase 3
2
catalysts ytd
2
approvals ytd
0
recalls ytd
0

Pipeline(6)

pipeline depth6 products
Phase 3: 2Marketed: 4
2Phase 34Marketed
Marketed
givosiran
Acute Intermittent Porphyria
Marketed
lumasiran
Primary Hyperoxaluria Type I
Marketed
patisiran
Familial Amyloid Neuropathies
Marketed
vutrisiran
Familial Amyloid Cardiomyopathy
Phase 3
nucresiran
Familial Amyloid Cardiomyopathy
Phase 3
zilebesiran sodium
Hypertension

📅 Upcoming

Oct 29, 2026
earnings
$ALNY229.30-5.49%
in 2mo
ALNYLAM PHARMACEUTICALS, INC. earnings
ALNYLAM PHARMACEUTICALS, INC.
→

🕒 Recent(90d)

nothing in the last 90 days
view all catalysts →

Active trials

  • phase2A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiranrecruitingn=93
  • phase3TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathyrecruitingn=125
  • phase2A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)recruitingn=58
  • phase1A Study to Evaluate ALN-6222 in Participants With Obesityrecruitingn=88
  • phase2HMBeacon: A Phase 2 Study to Evaluate ALN-6400 in Adult and Adolescent Female Patients With VWD and HMBrecruitingn=24
  • phase2A Study to Evaluate ALN-2232 in Participants With Obesityrecruitingn=156
  • phase1A Study to Evaluate ALN-4285 in Adult Healthy Volunteersrecruitingn=76
  • —Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Programrecruitingn=10
more trials →

Insider activity

source: SEC Form 4

open-market buys + sells

  • Apr 6, 26SELLMcLaughlin Melissa· Chief Human Resources Officer909 sh @ $329.76−$300K↗
  • Apr 6, 26SELLMcLaughlin Melissa· Chief Human Resources Officer829 sh @ $330.46−$274K↗
  • Apr 6, 26SELLMcLaughlin Melissa· Chief Human Resources Officer293 sh @ $331.89−$97K↗
  • Apr 6, 26SELLMcLaughlin Melissa· Chief Human Resources Officer199 sh @ $333.94−$66K↗
  • Apr 6, 26SELLMcLaughlin Melissa· Chief Human Resources Officer56 sh @ $320.14−$18K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer359 sh @ $317.44−$114K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer265 sh @ $316.61−$84K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer245 sh @ $322.86−$79K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer224 sh @ $321.64−$72K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer209 sh @ $318.47−$67K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer147 sh @ $320.62−$47K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer86 sh @ $319.69−$27K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer81 sh @ $323.64−$26K↗
  • Apr 2, 26SELLMcLaughlin Melissa· Chief Human Resources Officer8 sh @ $325.49−$3K↗
  • Mar 5, 26SELLGarg Pushkal· EVP Chief R&D740 sh @ $323.55−$239K↗
  • Mar 5, 26SELLGarg Pushkal· EVP Chief R&D654 sh @ $322.33−$211K↗
  • Mar 5, 26SELLGarg Pushkal· EVP Chief R&D510 sh @ $324.59−$166K↗
  • Mar 5, 26SELLGarg Pushkal· EVP Chief R&D500 sh @ $326.08−$163K↗
  • Mar 5, 26SELLFitzgerald Kevin Joseph· CSO & EVP, Head of Research233 sh @ $323.25−$75K↗
  • Mar 5, 26SELLFitzgerald Kevin Joseph· CSO & EVP, Head of Research153 sh @ $326.24−$50K↗
🐶 Hiring Signal
next earnings Oct 29, 2026
No open roles indexed yet — view ALNYLAM PHARMACEUTICALS, INC. jobs →

News

  • After tasting IPO success, Hemab’s CEO seeks ‘flavor of a multi-product coagulation company’
    With the post-IPO quiet period having come to an end, CEO Benny Sørensen, M.D., Ph.D., was free to sit down with Fierce to map out Hemab’s future.
    fiercebiotech · 9d ago
  • Alnylam absorbs $10.8B blowback after cutting full-year guidance for TTR franchise
    Alnylam’s revenue cut “may create a near term credibility overhang and could “raise questions on peak sales potential, even if there’s tailwinds in the competitive landscape,” according to Stifel.
    biospace · 20d ago
  • AstraZeneca, Ionis drug fails big heart disease study in major setback
    Eplontersen’s failure in transthyretin-mediated amyloidosis cardiomyopathy caught Wall Street analysts by surprise and boosted the outlook of rival drugs from Alnylam and BridgeBio Pharma.
    biopharma_dive · 1mo ago
  • Biotech investors gamble on M&A. Some drugmakers are betting on themselves instead.
    Young biotechs usually get acquired instead of profitably selling their own medicines. A growing number are proving they can, which could make the sector more broadly appealing to investors, some say.
    biopharma_dive · 3mo ago
identifiers
ticker
$ALNY
SEC CIK
0001178670
country
US
source
sec_tickers
top tags
Cardiology1Hypertension1
mentioned in
4news items
entity-linker matched
Data sources
SEC EDGAR
last refreshed 10m ago
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