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  • What’s next for VEGF? #ASCO26 offered clues, but answers will have to wait
    CHICAGO — Not long ago, there were hopes that a new class of cancer drugs would repeat the success of Keytruda. Instead, it seems more likely they could end up making up for its weaknesses. Many ...
    Endpoints · 1mo ago↗ source
  • STAT+: Radiopharmaceutical shows promise in post-Pluvicto setting
    Abivax's ulcerative colitis data, Fulcrum's scrapped sickle cell drug, and more biotech news from The Readout
    STAT · 1mo ago↗ source
  • Male contraception startup closes $92.5M Series B; Novartis bets on actinium
    💸 Funding male contraception: Contraline closed a $92.5 million Series B financing to support a Phase 3 study of a male contraceptive dubbed NES/T. The daily treatment is a gel rubbed on the shoul…
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Endpoints · 1mo ago
↗ source
  • Travere pays Everest $112M upfront to grow rare kidney disease pipeline
    Travere Therapeutics is enlisting the help of China-based Everest Medicines to bolster its rare kidney disease pipeline beyond its approved medicine Filspari. The San Diego biotech is doling out $1…
    Endpoints · 1mo ago↗ source
  • Legend Biotech shares first in vivo CAR-T data, its next act after Carvykti
    Legend Biotech’s long-awaited first showing of in vivo CAR-T data is here, fueling momentum in the growing field. Legend reported results Tuesday on 12 lymphoma patients from an investigator-initia…
    Endpoints · 1mo ago↗ source
  • STAT+: Pharmalittle: We’re reading about a Lilly threat to 340B hospitals, Ebola vaccine funding, and more
    Lilly gave hospitals participating in a federal drug discount program five days to submit claims data or it will stop the price breaks
    STAT · 1mo ago↗ source
  • How one state’s medical meal program lowered health care costs
    Medicaid work requirements, fast-tracked funding for experimental Ebola vaccines, and more health news from Morning Rounds
    STAT · 1mo ago↗ source
  • #ASCO26: Celcuity plans another FDA filing after positive breast cancer readout
    Celcuity said a combination regimen with its experimental drug gedatolisib doubled patients' likelihood of survival without disease progression or death in a late-stage breast cancer trial. Executi…
    Endpoints · 1mo ago↗ source
  • Citing 'dangerous deals,' lawmakers propose China restrictions
    A bipartisan group of Michigan lawmakers released a new bill that could greatly stifle the booming cross-border deals spree between Chinese and American biotechs. Rep. John Moolenaar (R-MI) and Rep…
    Endpoints · 1mo ago↗ source
  • #ASCO26: Roche details narrow failure of breast cancer pill trial
    Back in March, Roche revealed that the breast cancer pill on which it had pinned billion-dollar sales expectations had failed in a pivotal Phase 3 trial. Data presented Tuesday at ASCO reveal ...
    Endpoints · 1mo ago↗ source
  • Fulcrum ends sickle cell ambitions following regulatory feedback, will seek exit
    Fulcrum Therapeutics is scrapping its sole clinical-stage medicine after feedback from the FDA that referenced a recently pulled cancer drug from Ipsen. Fulcrum had planned to enter a registrationa…
    Endpoints · 1mo ago↗ source
  • Cancer cases weigh down Abivax’s Phase 3 maintenance data in ulcerative colitis
    Abivax has proclaimed that its maintenance trial in ulcerative colitis delivered “landmark” results, and the drug's safety profile has previously been one of its main potential selling points. But…
    Endpoints · 1mo ago↗ source
  • Praxis sinks on late-stage study fail for seizure pill, halts second trial
    Praxis Precision Medicines has had a decent run over the past eight months or so, with two major clinical wins. But on Monday, the company disclosed a late-stage failure for its investigational sei…
    Endpoints · 1mo ago↗ source
  • Obesity care startup Ilant Health raises $15M
    Ilant Health has raised $15 million in a Series A funding round to expand its personalized approach to treating obesity. Ilant is one of many virtual care companies competing to help employers and…
    Endpoints · 1mo ago↗ source
  • Updated: Allen Institute launches $400M effort to turn brain atlas lessons into medicines
    A Seattle-based nonprofit known for basic brain research is launching a $400 million initiative to translate its knowledge into drug development for neurodegenerative diseases, including Alzheimer'…
    Endpoints · 1mo ago↗ source
  • Opinion: The virtual end of the doctor’s office waiting room
    It’s time to rethink and redesign how patients enter the health care system altogether, writes emergency physician Iyesatta Massaquoi Emeli.
    STAT · 1mo ago↗ source
  • STAT+: Online care is caught in the crossfire as states crack down on corporate medicine
    Growing legislative scrutiny across multiple states targets the corporate structure underlying most direct-to-consumer telehealth businesses.
    STAT · 1mo ago↗ source
  • STAT+: Trump administration releases rules for new Medicaid work requirements
    States are racing to implement the new requirements by the start of next year.
    STAT · 1mo ago↗ source
  • STAT+: Eli Lilly warns hospitals to submit claims data in the next five days or lose their 340B drug discounts
    Eli Lilly has told more than 1,000 hospitals participating in the 340B drug discount program to submit claims data over the next five days — or lose price breaks.
    STAT · 1mo ago↗ source
  • STAT+: Global coalition to fast-track three vaccines targeting Ebola outbreak with $62 million in funding
    With no licensed vaccines available to protect against the Ebola virus currently spreading in the Congo, efforts are underway to fast-track development of at least three vaccines.
    STAT · 1mo ago↗ source
  • STAT+: Abivax ulcerative colitis drug shows strong efficacy, but cases of cancer raise concerns
    Abivax said its experimental treatment for ulcerative colitis showed significant efficacy in a closely watched trial, but shares of the company tanked on safety concerns.
    STAT · 1mo ago↗ source
  • STAT+: At ASCO, talk of barriers to cancer care, new treatments, and other big takeaways
    Here is some of what you may have missed from the world's largest cancer research meeting.
    STAT · 1mo ago↗ source
  • STAT+: At the world’s largest cancer research meeting, data briefly took a backseat to grief
    At the world's largest cancer research meeting, new data were plentiful. But this year, there was also a focus on grief.
    STAT · 1mo ago↗ source
  • The cost of a PRV is twice as high as it was three years ago — and it’s likely to stay that way
    How much is a regulatory shortcut worth? The cost of a priority review voucher, which shortens the FDA’s standard review time by about four months, has roughly doubled in the last few years. The FD…
    Endpoints · 1mo ago↗ source
  • Epigenetic editing shows promise against chronic hep B infections
    A new method of CRISPR-based gene editing shows promise in curtailing chronic hepatitis B infections. Its twist is to silence disease-causing genes without altering the underlying DNA. Tune Therape…
    Endpoints · 1mo ago↗ source