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STAT805 Endpoints604 BioPharma Dive231 onclive165 Fierce Biotech74 BioSpace71 raps32 fda press20 globenewswire health

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Clinical Implementation and Surveillance Strategies
onclive · 2mo ago↗ source
Case Introduction and ctDNA as Emerging Risk Factor
onclive · 2mo ago↗ source
ASCO 2026: All Eyes Are on Daraxonrasib and a Wave of Novel Targeted Therapies in GI Malignancies
Ahead of the 2026 ASCO Annual Meeting, experts in GI malignancies share the most anticipated research being presented during the meeting.
onclive · 2mo ago↗ source

page 31 of 45

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Infectious Disease4

MET Alterations in NSCLC: Amplification, Mutations, and Therapeutic Strategies

Decode MET-altered lung cancer: amplification, exon 14 skipping and co-mutations, plus evolving targeted therapies and tumor board insights.

onclive · 2mo ago↗ source

Planned HERIZON-GEA-01 Analyses and the Doublet-vs-Triplet Question

New HER2+ gastric cancer data show triplet immunotherapy boosts survival and durable responses, hinting immune activation beyond HER2 targets.

onclive · 2mo ago↗ source

HERIZON-GEA-01 Efficacy Results and Interpretation of Duration of Response

HORIZON-GA01 shows zenidatamab regimens significantly improve survival in HER2-positive gastric cancer, while PD-L1 testing differences raise key questions for treatment choice.

onclive · 2mo ago↗ source

Five-year survival with tebentafusp in previously untreated metastatic uveal melanoma in a phase 3 trial (CT029)

Five-year Phase III data show tebentafusp doubles survival in metastatic uveal melanoma, with ctDNA response predicting benefit beyond imaging and progression.

onclive · 2mo ago↗ source

Emerging Biomarkers in NSCLC: TROP2 Scoring and MTAP Loss

How Trop2 and MTAP-loss reshape NSCLC therapy, with AI pathology refining ADC response prediction and guiding trial referrals.

onclive · 2mo ago↗ source

STAT+: Three years of declining overdose deaths begets cautious optimism and some concerns

The next FDA leader, how the CDC is responding to hantavirus, and more health news from Morning Rounds

STAT · 2mo ago↗ source

STAT+: Biogen’s tau-targeting Alzheimer’s drug posts mixed results in mid-stage study

Biogen is moving its tau-targeting Alzheimer's drug into Phase 3 studies, despite mixed data from a Phase 2 trial.

STAT · 2mo ago↗ source

STAT+: CREATE Medicines, a biotech company developing CAR-T therapies, raises $122 million

CREATE Medicines has a new name, an expanded pipeline, and now fresh funding to propel the company’s first CAR-T candidates through human trials.

STAT · 2mo ago↗ source

STAT+: Regenxbio says Duchenne gene therapy succeeded in clinical trial, paving way for FDA submission

Regenxbio said its experimental gene therapy for Duchenne muscular dystrophy succeeded in a trial, paving the way for a submission to the FDA.

STAT · 2mo ago↗ source

STAT+: ‘No drama’ Diamantas should serve biotech well as acting FDA chief

Kyle Diamantas, the acting commissioner of the FDA, is expected to be a drama-free, stabilizing caretaker at the top of the agency.

STAT · 2mo ago↗ source

STAT+: Treatment for alcohol addiction is undergoing a seismic shift. Many say it’s overdue

The surging popularity of alternatives to Alcoholics Anonymous represents a seismic shift in the alcohol treatment landscape. Many say it's overdue.

STAT · 2mo ago↗ source

Opinion: Using AI in addiction medicine could be particularly risky

"AI can make great strides in medical decision support, but unfiltered interaction between agent and patient is dangerous," writes Steve D. Klein.

STAT · 2mo ago↗ source

Evolving Oral SERD Research Seeks to Redefine Treatment Strategies in Hormone Receptor+ Breast Cancer

Breast cancer experts discuss the nuances of ESR1 mutations and oral SERD use in hormone receptor–positive breast cancer.

onclive · 2mo ago↗ source

Immunotherapy Advances in Upfront SCAC Expose Need for Better Second-Line Strategies

Aparna R. Parikh, MD, emphasizes the feasibility of immunotherapy trials in SCAC and the need for better treatment options in the second line and beyond.

onclive · 2mo ago↗ source

Hantavirus risk remains low, CDC says, citing its ‘playbook’ response

Despite rising concern about the hantavirus outbreak on a cruise ship, two CDC doctors say the risk to the public remains low.

STAT · 2mo ago↗ source

Dr Loghavi on the Significance of Updated WHO Diagnostic Criteria for AML in Clinical Practice

Sanam Loghavi, MD, discusses updated WHO diagnostic criteria for acute myeloid leukemia and its significance for diagnoses and treatment selection.

onclive · 2mo ago↗ source

Officials say $1.3 billion in Medicaid money to California will be deferred over suspicions of fraud

Vice President JD Vance announced a $1.3 billion deferral in Medicaid reimbursements to California, as part of an initiative to root out fraud in federal health programs.

STAT · 2mo ago↗ source

Opinion: The hantavirus is a wake-up call. Will the Trump administration answer it?

Arriving in the isolation ward of a biocontainment hospital is an unsettling, scary experience. In 2014, I spent 19 days in one while being treated for Ebola, watching the news…

STAT · 2mo ago↗ source

FDA Approves Decitabine/Cedazuridine Plus Venetoclax in Newly Diagnosed AML

The FDA has approved oral decitabine/cedazuridine plus venetoclax for newly diagnosed AML unfit for intensive chemo, based on phase 2 ASCERTAIN-V data.

onclive · 2mo ago↗ source

FDA Approves Sonrotoclax for Relapsed/Refractory Mantle Cell Lymphoma

The FDA granted accelerated approval to sonrotoclax for relapsed/refractory mantle cell lymphoma after at least 2 lines of systemic therapy.

onclive · 2mo ago↗ source

Dr Dinardo on the FDA Approval of Decitabine/Cedazuridine Plus Venetoclax in AML

Courtney D. DiNardo, MD, MSCE, discusses the FDA approval of decitabine/cedazuridine plus venetoclax in acute myeloid leukemia.

onclive · 2mo ago↗ source

Opinion: Hospitals are silencing doctors online, and it’s fueling the health misinformation crisis

Hospitals and health systems need to loosen the reins and let physicians combat social media misinformation, writes Adam Goodcoff.

STAT · 2mo ago↗ source