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  • 2026 Orphan Drugs Report: A safe(r) passage amid stormy waters?
    <p>Orphan drugs remain commercially durable, strategically relevant and supported by a strong pipeline</p>
    BioPharma Dive · 1mo ago↗ source
  • Oculis’ eye drops for diabetic macular edema flunk Phase 3 test
    Oculis saw its stock plummet after reporting that its investigational eye drops for diabetic macular edema (DME) did not succeed in a pair of Phase 3 trials. After a year, its eye drop called OCS…
    Endpoints · 1mo ago↗ source
  • #ASCO26: Yes, Revolution Medicines' pancreatic cancer data are that good
    CHICAGO — When oncologist Brian Wolpin saw the positive results from Revolution Medicines' pivotal pancreatic cancer study for the first time, he was rendered speechless, he told Endpoints News.…
    Endpoints
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Hematology6
Pulmonology5
Infectious Disease4
Ophthalmology3
Dermatology2
· 1mo ago
↗ source
  • #ASCO26: Summit, Akeso drug reduces death by 34% in China lung cancer study
    CHICAGO — The leading drug in biopharma's hottest immunotherapy race reduced the risk of death by 34% in previously untreated Chinese lung cancer patients, compared to standard immunotherapy plus c…
    Endpoints · 1mo ago↗ source
  • Akeso, Summit drug extends survival in closely watched lung cancer trial
    <figure><div><img src="https://imgproxy.divecdn.com/U1p_j9BDqJ48JLk77g8bxOnzXIh5YVNKqCXZdq4xNwI/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xNDcxMDQzNjg0LmpwZ…
    BioPharma Dive · 1mo ago↗ source
  • ‘Unprecedented’ Revolution data point to paradigm shift in pancreatic cancer
    <figure><div><img src="https://imgproxy.divecdn.com/WEayUdfuHXoOw2FpmsOFLF4yn7KYNOFOwzm5w7xXaT4/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMzE4Mjc5OTExLmpwZ…
    BioPharma Dive · 1mo ago↗ source
  • #ASCO26: Personalized cancer vaccines may help brain cancer patients live longer
    Personalized cancer vaccines might make notoriously deadly brain cancers more susceptible to immunotherapy and possibly prolong survival for some patients, according to new research from the Dana-F…
    Endpoints · 1mo ago↗ source
  • #ASCO26: Grail’s cancer blood test isn’t ready for widespread use, experts say
    CHICAGO — Grail's blood test, which it has pitched as a way to spot a variety of cancers early in their growth, still isn't ready to be used as a regular screening tool, experts not involved ...
    Endpoints · 1mo ago↗ source
  • Can AI do scientific research?; The 'magic bullet' search has faded in immunotherapy; and more
    Welcome back to Endpoints Weekly! We’ve got a team of reporters on the ground in Chicago this weekend for ASCO, including my fellow Weekly co-author Max Gelman. If you haven’t already, check out Ma…
    Endpoints · 1mo ago↗ source
  • At ASCO, Merck makes case for a ‘cornerstone’ cancer drug
    <p>Study results accrued so far are giving Merck greater conviction that the therapy, licensed from a China-based biotech, was worth placing into a sprawling Phase 3 program.</p>
    BioPharma Dive · 1mo ago↗ source
  • Bristol Myers unveils data for one of its next-gen blood cancer drugs
    <figure><div><img src="https://imgproxy.divecdn.com/aUhcesS0eCO3NThNNqPfIC_gM2-0lSalzL7WEg-RP7g/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy02ODA4MDQ3ODAuanBn.…
    BioPharma Dive · 1mo ago↗ source
  • Next FDA user fee deal is under review at the White House
    The White House is examining a deal recently reached by the FDA and the biopharma industry that sets the prescription drug user fees that the sector will pay the agency from 2028 through 2032, sour…
    Endpoints · 1mo ago↗ source
  • Post-Hoc: Lilly gets more secretive and hides Phase 1 pipeline
    Eli Lilly is getting more opaque as it gets bigger. Earlier this year, the drugmaker stopped disclosing its early-stage pipeline work. Its Phase 1 projects vanished from the company’s earnings pr…
    Endpoints · 1mo ago↗ source
  • Replimune takes third swing at cancer drug approval following ‘productive’ FDA talks
    <figure><div><img src="https://imgproxy.divecdn.com/KkNxfSBTkY2VjB8ICSuee0jTuqLQfv0D9hMURCyAiqU/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMjI3NzEwNDcyX1h1c…
    BioPharma Dive · 1mo ago↗ source
  • AstraZeneca seeks path for failed antibody; Imfinzi, Tremfya get label expansions
    🔎 AstraZeneca narrows path for failed antibody: The company announced last summer that its monoclonal antibody anselamimab missed the primary endpoint in a pair of Phase 3 trials for patients with…
    Endpoints · 1mo ago↗ source
  • Replimune will again submit its melanoma drug for approval
    Third time’s the charm? Replimune announced Friday that it will submit its advanced melanoma drug RP1 for FDA review after two prior rejections. It said it has had new discussions with ...
    Endpoints · 1mo ago↗ source
  • Agios ends development of tebapivat in low-risk MDS following subpar results
    Agios Pharmaceuticals has said it will stop developing its rare blood disorder drug for certain patients with myelodysplastic syndromes (MDS) due to disappointing Phase 2b data. The biotech’s pyr…
    Endpoints · 1mo ago↗ source
  • Allogene CEO to step down; Agios drug fails key test
    <figure><div><img src="https://imgproxy.divecdn.com/idsdMAHsPbXObDUtQW2qRG7uveBUVv6HCTn9NTtlDOI/g:nowe:0:0/c:1207:682/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0x…
    BioPharma Dive · 1mo ago↗ source
  • Can a chaotic FDA still deliver on faster drug development?
    <figure><div><img src="https://imgproxy.divecdn.com/GjzgQSCxYItE_nvCVcgr1dRWi34d0viitteF7G59vHs/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0yMjAxMjA4MDM3LmpwZ…
    BioPharma Dive · 1mo ago↗ source
  • #ASCO26: Bristol Myers details Phase 3 trial win for Pomalyst successor
    Bristol Myers Squibb’s next-gen multiple myeloma drug cut the risk of disease progression or death for certain patients by 52% when added on top of a combination treatment regimen. The New Jersey…
    Endpoints · 1mo ago↗ source
  • Pfizer, Innovent strike $10B cancer drug deal
    <figure><div><img src="https://imgproxy.divecdn.com/MR_ueNISGsuP2HU9tITuSVUs34rcuaidMyQcZYbmwDU/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS8yWDJIQ0U1LmpwZw==.webp"/></div></f…
    BioPharma Dive · 1mo ago↗ source
  • David Chang to hand over the reins at Allogene; Ex-Esperion CEO gets started at Phlow
    Longtime Allogene CEO David Chang will be stepping down at the end of June. Chang has served as the company’s CEO for the past eight years and will be succeeded by ...
    Endpoints · 1mo ago↗ source
  • Pfizer strikes Innovent deal worth up to $10.5B for a dozen cancer programs
    On the eve of this year’s ASCO annual meeting, Pfizer said it is teaming up with China’s Innovent Biologics to advance a portfolio of 12 early-stage antibody-drug conjugates and multi-specific anti…
    Endpoints · 1mo ago↗ source
  • Lilly obesity meds Foundayo and Zepbound to gain CVS coverage
    Eli Lilly’s flagship obesity medications will be included in CVS Caremark formularies, likely boosting sales in the most competitive commercial drug market. The company announced Thursday that it…
    Endpoints · 2mo ago↗ source
  • GSK, Ionis unveil data for hepatitis B drug touted as ‘functional cure’
    <figure><div><img src="https://imgproxy.divecdn.com/vUSMTsRzVRhCroTDXLlF1SxrsYDX4vu6Ncn85SRCThk/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMjEwNTY3ODgwLmpwZ…
    BioPharma Dive · 2mo ago↗ source