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  • Eli Lilly issues data sharing ultimatum to 340B hospitals
    <figure><div><img src="https://imgproxy.divecdn.com/8nTrHlsFTcngJswJxr_8afos9dxh_YxQE6LZmgMA2_I/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0yMDkyNDczMjEzX2VHa…
    BioPharma Dive · 1mo ago↗ source
  • Fulcrum exploring a potential sale after FDA sidelined its sickle cell drug
    <figure><div><img src="https://imgproxy.divecdn.com/NkRGM2WlVG_bih055HG7zy8PbwZNjna8pIs5Yzt_9MI/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0yMTcwOTEzMjEwLmpwZ…
    BioPharma Dive · 1mo ago↗ source
  • What’s next for VEGF? #ASCO26 offered clues, but answers will have to wait
    CHICAGO — Not long ago, there were hopes that a new class of cancer drugs would repeat the success of Keytruda. Instead, it seems more likely they could end up making up for its weaknesses. Many ...
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Endpoints · 1mo ago
↗ source
  • Male contraception startup closes $92.5M Series B; Novartis bets on actinium
    💸 Funding male contraception: Contraline closed a $92.5 million Series B financing to support a Phase 3 study of a male contraceptive dubbed NES/T. The daily treatment is a gel rubbed on the shoul…
    Endpoints · 1mo ago↗ source
  • Travere pays Everest $112M upfront to grow rare kidney disease pipeline
    Travere Therapeutics is enlisting the help of China-based Everest Medicines to bolster its rare kidney disease pipeline beyond its approved medicine Filspari. The San Diego biotech is doling out…
    Endpoints · 1mo ago↗ source
  • Legend Biotech shares first in vivo CAR-T data, its next act after Carvykti
    Legend Biotech’s long-awaited first showing of in vivo CAR-T data is here, fueling momentum in the growing field. Legend reported results Tuesday on 12 lymphoma patients from an investigator-init…
    Endpoints · 1mo ago↗ source
  • AbiVax falls as safety worries cloud ‘landmark’ immune drug results
    <figure><div><img src="https://imgproxy.divecdn.com/xa_T0oT9Hj8F-wJjKfJeFkbn4Yqp_lT58dL0S4GszxY/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy02MjEzNjQ4MDJfMS5qc…
    BioPharma Dive · 1mo ago↗ source
  • #ASCO26: Celcuity plans another FDA filing after positive breast cancer readout
    Celcuity said a combination regimen with its experimental drug gedatolisib doubled patients' likelihood of survival without disease progression or death in a late-stage breast cancer trial. Execu…
    Endpoints · 1mo ago↗ source
  • Citing 'dangerous deals,' lawmakers propose China restrictions
    A bipartisan group of Michigan lawmakers released a new bill that could greatly stifle the booming cross-border deals spree between Chinese and American biotechs. Rep. John Moolenaar (R-MI) and R…
    Endpoints · 1mo ago↗ source
  • #ASCO26: Roche details narrow failure of breast cancer pill trial
    Back in March, Roche revealed that the breast cancer pill on which it had pinned billion-dollar sales expectations had failed in a pivotal Phase 3 trial. Data presented Tuesday at ASCO reveal ...
    Endpoints · 1mo ago↗ source
  • Fulcrum ends sickle cell ambitions following regulatory feedback, will seek exit
    Fulcrum Therapeutics is scrapping its sole clinical-stage medicine after feedback from the FDA that referenced a recently pulled cancer drug from Ipsen. Fulcrum had planned to enter a registratio…
    Endpoints · 1mo ago↗ source
  • Cancer cases weigh down Abivax’s Phase 3 maintenance data in ulcerative colitis
    Abivax has proclaimed that its maintenance trial in ulcerative colitis delivered “landmark” results, and the drug's safety profile has previously been one of its main potential selling points. But…
    Endpoints · 1mo ago↗ source
  • Praxis sinks on late-stage study fail for seizure pill, halts second trial
    Praxis Precision Medicines has had a decent run over the past eight months or so, with two major clinical wins. But on Monday, the company disclosed a late-stage failure for its investigational s…
    Endpoints · 1mo ago↗ source
  • ASCO ‘26: Bispecifics vs. ADCs, a ‘RAS’ revolution and a step change in prostate cancer
    <p>At the year’s biggest cancer meeting, a high-stakes clash between two popular drug classes erupted, and scientists made headway against a once-insurmountable foe.</p>
    BioPharma Dive · 1mo ago↗ source
  • Obesity care startup Ilant Health raises $15M
    Ilant Health has raised $15 million in a Series A funding round to expand its personalized approach to treating obesity. Ilant is one of many virtual care companies competing to help employers an…
    Endpoints · 1mo ago↗ source
  • Why US-manufactured pharmaceutical packaging equipment matters
    <p>As manufacturers modernize operations, the origin of their equipment is a strategic consideration.</p>
    BioPharma Dive · 1mo ago↗ source
  • Updated: Allen Institute launches $400M effort to turn brain atlas lessons into medicines
    A Seattle-based nonprofit known for basic brain research is launching a $400 million initiative to translate its knowledge into drug development for neurodegenerative diseases, including Alzheimer'…
    Endpoints · 1mo ago↗ source
  • RallyBio tries again for reverse merger, this time with Avenzo
    <figure><div><img src="https://imgproxy.divecdn.com/jnFfJ5RS6xuGM4eSgKJWCwh47VZKvpGyBiu3dqhXngw/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMjIwOTA5MTA5LmpwZ…
    BioPharma Dive · 1mo ago↗ source
  • The cost of a PRV is twice as high as it was three years ago — and it’s likely to stay that way
    How much is a regulatory shortcut worth? The cost of a priority review voucher, which shortens the FDA’s standard review time by about four months, has roughly doubled in the last few years. The…
    Endpoints · 1mo ago↗ source
  • Epigenetic editing shows promise against chronic hep B infections
    A new method of CRISPR-based gene editing shows promise in curtailing chronic hepatitis B infections. Its twist is to silence disease-causing genes without altering the underlying DNA. Tune Thera…
    Endpoints · 1mo ago↗ source
  • Shionogi wins US approval for first pill to prevent Covid following exposure
    Japan's Shionogi on Monday said it won FDA approval for its oral antiviral to prevent Covid‑19 in adults and children older than 12 years who have been in contact with someone ...
    Endpoints · 1mo ago↗ source
  • #ASCO26: Lilly's plenaries; Incyte's frontline data in lymphoma
    Two plenaries related to Lilly: Researchers detailed findings from an investigator-sponsored trial using Lilly’s CDK4/6 inhibitor Verzenio in a rare cancer called dedifferentiated liposarcoma, show…
    Endpoints · 1mo ago↗ source
  • Servier buys into muscular dystrophy with potentially $2.7B deal
    <figure><div><img src="https://imgproxy.divecdn.com/noY6Oanv5v-_yDQZKEqBBDkEKvecYGoj9vaCkgyW_q0/g:ce/rs:fill:1600:900:1/Z3M6Ly9kaXZlc2l0ZS1zdG9yYWdlL2RpdmVpbWFnZS9HZXR0eUltYWdlcy0xMjgxODMyMjUyX20yY…
    BioPharma Dive · 1mo ago↗ source
  • Agios licenses Oscotec drug; CEPI funds three potential Ebola vaccines
    🪪 Agios licenses Oscotec’s immune thrombocytopenia drug: Agios is paying $25 million upfront for exclusive global rights to Oscotec’s next-generation SYK inhibitor, called cevidoplenib. The South…
    Endpoints · 1mo ago↗ source
  • #ASCO26: Kelonia Therapeutics delivers an impressive in vivo CAR-T update
    CHICAGO — Eli Lilly in April signed an up to $7 billion deal to buy Kelonia Therapeutics, and now we know why. All 18 multiple myeloma patients who have received Kelonia’s in vivo CAR-T therapy ...
    Endpoints · 1mo ago↗ source