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Endpoints·2h ago·1 min read
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Amgen's Imdelltra plus AstraZeneca's Imfinzi cuts death risk by 58% in small cell lung cancer Phase 3 trial

Oct 24, 2026·read at Endpoints ↗Positive readoutPositive

Amgen reported results from a Phase 3 trial evaluating its investigational therapy Imdelltra in combination with AstraZeneca’s immunotherapy Imfinzi in patients with small cell lung cancer.

The study, conducted in the first‑line maintenance setting, showed that adding Imdelltra reduced the risk of death by 58% compared with Imfinzi alone.

The magnitude of benefit exceeds the pre‑specified benchmark for overall survival, suggesting the combination could become a new standard for this patient population.

The data were presented at the European Society for Medical Oncology (ESMO) meeting in Madrid.

source

This writeup was produced by pharmadog from original reporting by Endpoints.

Original headline: “#ESMO26: Amgen's Imdelltra regimen more than halves risk of death in Phase 3 lung cancer trial”

read at Endpoints ↗
94 words · retrieved 1h ago
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companies & drugs in this story

companies
AMGEN4ASTRAZENECA2
drugs
durvalumab6IMDELLTRA4tarlatamab4
topics
Oncology4Pulmonology4NSCLC3

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