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Fierce Biotech·7h ago·1 min read
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Novo Nordisk signs $2.6 billion deal with China's Hengrui for oral GLP-1/GIP candidate

Sep 29, 2026·read at Fierce Biotech ↗DealPositive

Novo Nordisk announced a licensing agreement with Chinese drugmaker Hengrui Pharmaceuticals, paying $300 million upfront for rights to a preclinical GLP-1/GIP dual-receptor agonist.

The candidate, called HRS-1596, is designed for once-weekly oral dosing and aims to suppress appetite, stimulate insulin secretion and improve insulin sensitivity for obesity, type 2 diabetes and other metabolic diseases.

Hengrui has secured Chinese regulatory clearance to begin phase 1 trials, and the agreement includes milestone payments that could lift the total value to $2.6 billion. Novo said the oral format could offer a convenience edge over current injectable GLP-1/GIP therapies.

source

This writeup was produced by pharmadog from original reporting by Fierce Biotech.

Original headline: “Novo agrees $2.6B deal for preclinical GLP-1/GIP drug from in-demand Hengrui”

read at Fierce Biotech ↗
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companies & drugs in this story

companies
NOVO18Novo Nordisk Inc3HENGRUI PHARMA2BRISTOLBRISTOL MYERS SQUIBBBRISTOL MYERS SQUIBB COELI LILLY COLEADINGLILLY
drugs
Obesity6Type 2 Diabetes4insulin4Insulin Sensitivity2ImmunologyMOUNJAROZEPBOUNDtirzepatide
topics
GLP-1 receptor10Type 2 Diabetes9Obesity8GIP receptor7Small Molecule6Big Pharma2Endocrinology & Metabolism2ImmunologyOncologyPulmonology

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