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Fierce Biotech·6h ago·1 min read
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ADARx upsizes Nasdaq IPO to $446M as City Therapeutics eyes public listing

Sep 25, 2026·read at Fierce Biotech ↗DealPositive

ADARx Pharmaceuticals, a San Diego-based RNA biotech, completed a Nasdaq initial public offering this morning, selling 26.3 million shares at $17 each.

The offering generated gross proceeds of about $446.3 million, exceeding the company’s earlier target of $350 million. Underwriters have an option to purchase an additional 3.9 million shares, which could add roughly $66.9 million to the total.

The company also expected a private-placement investment from partner AbbVie of around $100 million, though this was not highlighted in the latest release.

ADARx said the capital will fund its lead siRNA candidate agazisiran, which targets complement factor B and is in phase-2 trials for several complement-mediated kidney diseases and the rare blood disorder paroxysmal nocturnal hemoglobinuria.

source

This writeup was produced by pharmadog from original reporting by Fierce Biotech.

Original headline: “ADARx scores upsized $446M IPO, while fellow RNA biotech City maps out Nasdaq plans”

read at Fierce Biotech ↗
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companies & drugs in this story

companies
ADARx Pharmaceuticals Inc5ABBVIE3Ultragenyx Pharmaceutical Inc.2WM TECHNOLOGY, INC.2ALNYLAM PHARMACEUTICALS, INC.BAUSCH
drugs
Atrial FibrillationObesity
topics
siRNA15AMD3Nephrology3Hematology2Rare Disease2Atrial FibrillationIBD (Crohn's + UC)ImmunologyObesityOphthalmologymRNA Therapeutic

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