FDA Commissioner Marty Makary resigns, Kyle Diamantas named acting commissioner

The U.S. Food and Drug Administration announced that Commissioner Marty Makary will step down from his position. The agency said that Kyle Diamantas, who currently oversees food regulation, will serve as the acting commissioner while a permanent replacement is identified.

According to internal sources, a faction within the Department of Health and Human Services had been dissatisfied with Makary's leadership and had explored options to remove him for several months. The resignation appears to be the result of that internal pressure.

The leadership change comes as the FDA continues to manage a range of ongoing initiatives, including drug approvals and safety oversight, and may influence the agency's strategic direction in the coming months.