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  • Murder suspect plans psychiatric defense in killing of UnitedHealthcare CEO
    Luigi Mangione has told the court he will rely on a psychiatric defense, arguing that he was suffering from extreme emotional disturbance when he shot UnitedHealthcare chief Brian Thompson. If a j…
    STAT · 2mo agoNegative↗ source
  • Neumora ends development of navacaprant after failed Phase 3 depression trials; EnGene cuts half its workforce
    Neumora Therapeutics announced it will discontinue its kappa opioid receptor antagonist navacaprant after the drug missed its primary endpoints in two Phase 3 studies for major depressive disorder.…
    BioPharma Dive · 2mo agoNegative readoutNegative↗ source
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  • Eli Lilly to acquire non-opioid pain drug developer 4E Therapeutics, adding MNK inhibitor pipeline
    Eli Lilly announced it will purchase 4E Therapeutics, a biotech focused on non‑opioid pain treatments. The acquisition gives Lilly access to 4E’s experimental pipeline, including MNK inhibitors su…
    BioPharma Dive · 2mo agoDealPositive↗ source
  • Edgewise Therapeutics' experimental heart drug meets Phase 2 endpoints in cardiomyopathy trial
    Edgewise Therapeutics reported that its oral candidate EDG-7500 achieved the predefined goals of a Phase 2 study in both obstructive and non‑obstructive hypertrophic cardiomyopathy. The trial demo…
    BioPharma Dive · 2mo agoPositive readoutPositive↗ source
  • Medicare to Cover Obesity Drugs for Adults 65+ Starting Next Month
    Medicare will begin covering prescription weight‑loss medications for beneficiaries aged 65 and older starting next month, marking the first time the program includes such drugs. The coverage is p…
    STAT · 2mo agoRegulatoryPositive↗ source
  • Biotech Converts Failed Trial Data into AI Model
    A biotech startup recently faced a setback when a clinical trial did not achieve its primary goals. Rather than discarding the results, the company chose to analyze the data for new insights. The…
    STAT · 2mo agoPositive↗ source
  • Express Scripts and PCMA file lawsuits to block Tennessee FAIR Rx Act targeting PBM-owned pharmacies
    Express Scripts, a Cigna subsidiary, and the Pharmaceutical Care Management Association have filed separate lawsuits in federal court in Tennessee. The suits challenge the FAIR Rx Act, a law passe…
    BioPharma Dive · 2mo agoRegulatoryNeutral↗ source
  • FDA staff raise concerns over data for Moderna’s mFlusiva flu vaccine ahead of advisory panel
    FDA staff have examined the evidence for Moderna's mFlusiva, an mRNA flu vaccine, and highlighted shortcomings in the data submitted to the agency. The Food and Drug Administration will convene an…
    BioPharma Dive · 2mo agoRegulatoryNegative↗ source
  • Verge Labs launches AI tool to boost patient enrollment and trial efficiency; Moderna appoints new chief commercial officer
    Verge Labs announced a new artificial‑intelligence model designed to identify patients most likely to respond to a therapy, aiming to reduce dropout rates and increase the statistical power of clin…
    STAT · 2mo agoPositive↗ source
  • Verge Labs launches AI tool to improve neurology trial patient selection after ALS setback
    Verge Labs, formerly known as Verge Genomics, announced a new artificial intelligence model designed to address patient stratification challenges in neurology clinical trials. The company says the…
    STAT · 2mo agoPositive↗ source
  • Congress urged to swiftly reauthorize Pandemic and All-Hazards Preparedness Act
    Former assistant secretary for preparedness Craig Vanderwagen and former Senate staffer Jennifer Alton argue that the Pandemic and All-Hazards Preparedness Act needs prompt reauthorization. They no…
    STAT · 2mo agoRegulatoryNeutral↗ source
  • U.S. infant mortality hits record low in 2025, though still behind peer nations
    Preliminary CDC data show the United States recorded its lowest infant mortality rate ever in 2025. The rate fell to just under 5.4 deaths per 1,000 live births. That figure represents a modest de…
    STAT · 2mo agoPositive↗ source
  • US spends $360,000 storing contraceptives meant for African aid, with most supplies nearing expiration
    The U.S. government spent roughly $360,000 between January 2025 and March 2026 to keep millions of dollars worth of contraceptives in climate-controlled storage, according to a recent USAID Office…
    STAT · 2mo agoNeutral↗ source
  • Human Cell Atlas leadership ties to 10x Genomics spark conflict-of-interest concerns
    The International Human Cell Atlas Consortium is marking its 10-year anniversary with a meeting in Boston that brings together academic and industry leaders. Attention has turned to one of the pro…
    STAT · 2mo agoNegative↗ source
  • Alzheimer specialist admits she missed early signs in her own father, urging earlier detection
    A neurologist at the University of California, San Diego writes about her personal experience when her father began showing subtle cognitive changes that were missed. She recounts small mistakes a…
    STAT · 2mo agoNegative↗ source
  • Medicare to cover GLP-1 weight-loss drugs for seniors under temporary Trump-backed program
    Starting July 1, Medicare will make GLP-1 weight-loss drugs available to adults 65 and older at a cost of $50 per prescription through a new demonstration program. The initiative, called Bridge, i…
    STAT · 2mo agoRegulatoryNeutral↗ source
  • Medicare rule could bring subcutaneous Keytruda and Opdivo under price negotiations
    A federal rule proposed for 2029 aims to close a loophole that currently shields medicines moving from intravenous to subcutaneous administration from Medicare price negotiations. The Centers for M…
    BioPharma Dive · 2mo agoRegulatoryNegative↗ source
  • J&J's Talvey plus Darzalex Faspro cuts death risk by up to 53% in relapsed multiple myeloma
    Johnson & Johnson reported that a combination of its immunotherapy Talvey with Darzalex Faspro, with or without Pomalyst, significantly lowered the risk of death in patients with relapsed or refrac…
    BioPharma Dive · 2mo agoPositive readoutPositive↗ source
  • Newborn contracts preventable syphilis amid Pfizer emergency penicillin shortage and procedural delays
    In March 2026 a pregnant woman in Gila County, Arizona tested positive for syphilis. Doctors said she needed an injectable penicillin dose at least 30 days before delivery to avoid severe fetal com…
    STAT · 2mo agoRegulatoryNegative↗ source
  • FDA greenlights Colorado's plan to import prescription drugs from Canada to lower costs
    The FDA announced Monday that Colorado will be allowed to bring in certain prescription medicines from Canada, aiming to reduce drug prices for state residents. This decision makes Colorado the se…
    STAT · 2mo agoApprovalPositive↗ source
  • FDA greenlights Colorado plan to import prescription drugs from Canada to lower prices
    FDA announced Monday that Colorado will be allowed to import certain prescription medicines from Canada, making it the second state to receive such authorization after Florida. The move is intende…
    STAT · 2mo agoApprovalPositive↗ source
  • European trial registry shows under half of studies missing timely results, analysis says
    A new analysis of a major European clinical trial database found that fewer than half of the studies reported results within the legally required timeframe, and only 42% provided complete data. Th…
    STAT · 2mo agoRegulatoryNegative↗ source
  • Covid vaccine linked to 24% drop in overall cardiac events, study of 1 million veterans shows
    A new analysis of more than one million U.S. veterans indicates that receiving a Covid‑19 vaccine is associated with a substantial reduction in heart‑related problems. Researchers observed a roughl…
    STAT · 2mo agoPositive readoutPositive↗ source
  • Lilly reports early positive results for new JAK2 inhibitor in hard-to-treat myelofibrosis
    Lilly has incorporated a JAK2‑targeting drug originally discovered by Ajax Therapeutics after its recent acquisition. The experimental pill is intended for patients with myelofibrosis, a difficult‑…
    BioPharma Dive · 2mo agoPositive readoutPositive↗ source
  • Sanofi’s Tzield approved amid review dispute as Bicillin shortage hampers syphilis treatment
    An Arizona woman pregnant with syphilis could not receive timely treatment because of a worsening shortage of Bicillin, the injectable penicillin made by Pfizer. The shortage has raised concerns ab…
    STAT · 2mo agoRegulatoryNeutral↗ source