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  • Servier acquires Edgewise's muscular dystrophy assets for $1.55 billion
    Servier announced it will purchase the muscular dystrophy business from Edgewise Therapeutics. The deal involves an upfront payment of $1.55 billion, giving the French company rights to Edgewise's…
    Endpoints · 3mo agoDealPositive↗ source
  • AstraZeneca reports promising triplet therapy results in liver cancer subgroup
    AstraZeneca presented new data at ASCO 2026 showing that a regimen combining a targeted agent with two immunotherapies produced clinical benefit in a subset of liver cancer patients. The study eva…
    Endpoints · 3mo agoPositive readoutPositive↗ source
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  • Priority review voucher prices have doubled over three years, likely to remain high
    Recent reporting highlights that the price of FDA priority review vouchers has roughly doubled from three years ago. The vouchers provide a shortcut that can shave about four months off the agency…
    Endpoints · 3mo agoRegulatoryNeutral↗ source
  • CRISPR-based epigenetic editing shows promise in silencing hepatitis B genes
    A new CRISPR-based technique targets the epigenome to turn off genes that drive chronic hepatitis B infection, doing so without changing the underlying DNA sequence. Tune Therapeutics reported ear…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Shionogi receives FDA nod for first oral COVID-19 post-exposure prevention pill
    Shionogi announced that the U.S. Food and Drug Administration has granted approval for its oral antiviral designed to prevent COVID-19 after exposure. The product is indicated for adults and child…
    Endpoints · 3mo agoApprovalPositive↗ source
  • Agios pays $25 million for global rights to Oscotec’s SYK inhibitor cevidoplenib
    Agios Therapeutics announced it has secured an exclusive worldwide license for Oscotec’s experimental SYK inhibitor, cevidoplenib. Under the agreement, Agios will pay $25 million up front to Oscot…
    Endpoints · 3mo agoDealNeutral↗ source
  • Avenzo Therapeutics to go public via reverse merger with Rallybio after Candid partnership ends
    On June 1, 2026, Avenzo Therapeutics announced that it will become a publicly traded company through a reverse merger with Rallybio, securing a Nasdaq listing after its previous partner, Candid, en…
    Endpoints · 3mo agoDealPositive↗ source
  • Turn Therapeutics reports faster symptom relief in Phase 2 eczema trial
    Turn Therapeutics, a California biotech, disclosed interim results from its Phase 2 study of a topical treatment for atopic dermatitis. The analysis of 50 patients indicated that skin symptoms imp…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • J&J’s Erleada reduces metastasis or death risk by 20% in early‑stage prostate cancer study
    Johnson & Johnson presented data on its hormone therapy drug Erleada at the ASCO 2026 meeting. The study focused on men with early‑stage prostate cancer who received the drug around the time of sur…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Oculis’ investigational eye drop OCS-01 fails Phase 3 trials for diabetic macular edema, shares tumble
    Oculis announced that its experimental eye drop OCS-01 did not meet primary endpoints in two Phase 3 studies aimed at treating diabetic macular edema. The trials were intended to evaluate the drug…
    Endpoints · 3mo agoNegative readoutNegative↗ source
  • Eli Lilly licenses Hanmi's GLP-2 asset for $75 million upfront
    Eli Lilly has signed a licensing agreement with South Korean biotech Hanmi to acquire rights to a GLP-2 drug candidate, paying an upfront cash payment of $75 million. The deal marks Lilly's entry…
    Endpoints · 3mo agoDealNeutral↗ source
  • #ASCO26: Lilly's plenaries; Incyte's frontline data in lymphoma
    Two plenaries related to Lilly: Researchers detailed findings from an investigator-sponsored trial using Lilly’s CDK4/6 inhibitor Verzenio in a rare cancer called dedifferentiated liposarcoma, show…
    Endpoints · 3mo agoNeutral↗ source
  • Revolution Medicines' pancreatic cancer trial shows striking positive results
    At the American Society of Clinical Oncology meeting, Revolution Medicines presented data from its pivotal pancreatic cancer trial that impressed many observers. Oncologist Brian Wolpin described…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Summit Therapeutics' Akeso cuts death risk by 34% in Chinese lung cancer trial presented at ASCO 2026
    Summit Therapeutics reported at the ASCO 2026 meeting that its experimental drug Akeso lowered the risk of death by 34% for previously untreated lung cancer patients in China when compared with the…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Personalized vaccines show promise in extending survival for some brain cancer patients, Dana-Farber study finds
    Personalized cancer vaccines are being investigated as a way to make aggressive brain tumors more responsive to immunotherapy, according to new research from the Dana-Farber Cancer Institute. The…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Experts say Grail’s multi-cancer blood test not yet ready for routine screening
    At the ASCO 2026 meeting in Chicago, Grail presented its multi-cancer early detection blood test, which the company markets as a tool to identify several cancers at an early stage. Independent exp…
    Endpoints · 3mo agoNegative↗ source
  • Endpoints Weekly previews ASCO coverage, discusses AI in research and shifting immunotherapy strategies
    The weekly newsletter returns with a team of reporters stationed in Chicago for the upcoming ASCO meeting. It promises on‑the‑ground insights from the conference. One focus will be the role of art…
    Endpoints · 3mo agoNeutral↗ source
  • Bristol Myers reports 52% reduction in progression risk for next-gen multiple myeloma drug in Phase 3 trial
    Bristol Myers Squibb said its next-generation multiple myeloma therapy, positioned as a successor to Pomalyst, lowered the risk of disease progression or death by 52% when added to a standard combi…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Pfizer partners with China's Innovent Biologics on $10.5 billion deal for 12 early-stage cancer programs
    Pfizer announced a collaboration with Innovent Biologics of China to develop a suite of cancer therapies. The agreement covers up to 12 early-stage antibody‑drug conjugates and multi‑specific anti…
    Endpoints · 3mo agoDealPositive↗ source
  • White House reviews FDA's new prescription drug user fee agreement for 2028-2032
    The White House is currently reviewing a recently negotiated agreement between the FDA and the biopharma industry that determines the level of prescription-drug user fees for the period 2028 throug…
    Endpoints · 3mo agoRegulatoryNeutral↗ source
  • Eli Lilly stops disclosing Phase 1 pipeline, making early-stage projects invisible in earnings decks
    Eli Lilly has become more opaque as its size grows, choosing to stop public disclosure of its early-stage research efforts. The shift was noted earlier this year when the company removed Phase 1 pr…
    Endpoints · 3mo agoNegative↗ source
  • AstraZeneca explores options after anselamimab fails Phase 3, while Imfinzi and Tremfya receive label expansions
    AstraZeneca announced that its experimental monoclonal antibody anselamimab failed to meet the primary endpoint in two Phase 3 trials for a specific patient group. The company said it will explore…
    Endpoints · 3mo agoNegative readoutNeutral↗ source
  • Agios halts development of tebapivat for low-risk MDS after disappointing Phase 2b data
    Agios Pharmaceuticals announced it will discontinue development of its pyruvate kinase activator tebapivat for patients with low-risk myelodysplastic syndromes (MDS). The decision follows the relea…
    Endpoints · 3mo agoNegative↗ source
  • Allogene CEO David Chang to step down after eight years; former Esperion chief joins Phlow
    Longtime Allogene chief executive David Chang announced he will leave the role at the end of June, concluding an eight‑year tenure leading the cell‑therapy developer. The company said a successor…
    Endpoints · 3mo agoNeutral↗ source
  • Replimune to resubmit melanoma therapy RP1 to FDA after two prior rejections
    Replimune announced on Friday that it will again submit its advanced melanoma candidate, RP1, to the U.S. Food and Drug Administration for review. The company says the filing follows new discussion…
    Endpoints · 3mo agoRegulatoryNeutral↗ source