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  • Vertex makes $10B deal for commercial endocrinology biotech Crinetics
    Vertex Pharmaceuticals is making the largest acquisition in its history, beefing up its commercial portfolio with a $10 billion takeover of Crinetics Pharmaceuticals. The Monday afternoon deal fo…
    Endpoints · 20d ago↗ source
  • Obamacare rolls shrank dramatically in many states over the past year, new federal data shows
    States across the country saw steep drops in the number of people covered by the Affordable Care Act over the past year, according to new federal data.
    STAT · 20d ago↗ source
  • CMS proposes 340B cuts
    A proposed rule would cut the rates by which Medicare pays hospitals for 340B drugs by more than a third, reviving a similar policy introduced by the first Trump administration. CMS said on Thurs…
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Endpoints · 20d ago
↗ source
  • FDA approves 23 new drugs in first half, overcoming staff-cut concerns
    There's an answer emerging on the multibillion-dollar question of whether the Trump administration's gutting of FDA staff in April 2025 would slow down drug approvals: So far, so good. In the
    Endpoints · 20d ago↗ source
  • New CDER appointment elevates longtime GLP-1 reviewer
    Acting FDA CDER director Michael Davis has promoted a longtime FDA staffer as an acting deputy director at the drug center. Lisa Yanoff, an agency veteran with expertise in metabolic drug revie…
    Endpoints · 20d ago↗ source
  • STAT+: Online GLP-1 prescriptions are often fast, easy — and low on clinical oversight
    A new secret-shopper study found that GLP-1 prescriptions from telehealth sites aren't often backed by appropriate clinical care.
    STAT · 20d ago↗ source
  • Bristol Myers details Krazati confirmatory study failure in colorectal cancer
    While Americans geared up for the July 4 holiday, Bristol Myers Squibb laid out how a confirmatory trial for its drug Krazati failed in colorectal cancer. Patients taking Krazati plus another dru…
    Endpoints · 20d ago↗ source
  • Roche aims to bolster breast cancer pipeline with early-stage Astex deal
    Monday’s deal between Otsuka’s subsidiary Astex Pharmaceuticals and Roche’s subsidiary Genentech is of interest not because it is big money — the upfront fee is just $25 million — but because of wh…
    Endpoints · 20d ago↗ source
  • Apogee details path to $10.9B AbbVie deal; UK starts drug pricing pilot
    Plus news about Brii Biosciences. 💰 How AbbVie got Apogee: The Chicago-area drug giant snagged Apogee Therapeutics for $10.9 billion last month after years of talking with the biotech. AbbVie he…
    Endpoints · 20d ago↗ source
  • STAT+: Four major biotech updates to catch up on
    Anthropic CEO talks drug discovery, Medicare proposes steep 340B drug payment cuts, and more biotech news
    STAT · 20d ago↗ source
  • Salk Institute’s president on NIH cuts, ‘all in’ on AI, and the Year of the Brain
    SAN DIEGO — From the president’s office at the Salk Institute, Gerald Joyce has a quintessential California view of hang gliders soaring over the Pacific Ocean. It’s been a little more turbulent…
    Endpoints · 20d ago↗ source
  • STAT+: Pharmalittle: We’re reading about a Novartis acquisition, Republicans backing clinical trial diversity, and more
    Novartis is pushing deeper into antibody-drug conjugate development, paying $1.1 billion upfront to buy Myricx Bio
    STAT · 20d ago↗ source
  • The race for an Ebola therapy begins
    Male marathoners "hit the wall," mental health in 2026, and more Morning Rounds news
    STAT · 20d ago↗ source
  • Novartis commits $1.1B upfront to take Myricx Bio and its next-gen ADC platform
    Novartis said Monday it will be spending $1.1 billion upfront to buy Myricx Bio, which has an antibody-drug conjugate payload platform that could offer an edge over current approaches. The Swiss…
    Endpoints · 21d ago↗ source
  • Opinion: The smart way to regulate the peptide boom
    “The FDA should pursue a structured, clinician-guided framework” on popular peptides, writes former surgeon general Jerome Adams.
    STAT · 21d ago↗ source
  • Opinion: Stopping doctors from ordering unnecessary diagnostic tests requires a structural fix
    “The medical industry has spent enormous effort making more advanced tests but expended little effort learning how to use tests correctly,” writes Daniel Morgan.
    STAT · 21d ago↗ source
  • STAT+: GOP lawmakers push Trump’s FDA to make sure clinical trials are diverse
    Supporters say clinical trial diversity is about making sure drugs and devices work, not about DEI.
    STAT · 21d ago↗ source
  • STAT+: I spoke to Anthropic’s CEO about how AI may affect biotech. Here’s what I learned
    Call AI in biotech hype at your peril. There are real reasons that pharmaceutical companies are embracing this technology right now.
    STAT · 21d ago↗ source
  • What does content creation do to mental health?
    This year at Vidcon, I was struck by how much of the conference’s programming was dedicated to the mental health of content creators.
    STAT · 21d ago↗ source
  • Anthropic launches Claude Science; House China panel probes trial sites; and more
    Happy Fourth of July! We’ve got a handful of stories worth checking out before the backyard barbecue begins. But first: a reminder to submit your nominations for this year’s Women in Biopharma ...
    Endpoints · 23d ago↗ source
  • When clinical AI gets real
    We’re heading toward a future in which certain parts of medical care are delivered without any humans involved. Cadence, which raised a $100 million Series C last week, is betting that it can mak…
    Endpoints · 24d ago↗ source
  • Scribe Therapeutics files for IPO in test of appetite for early-stage biotechs
    Scribe Therapeutics filed for a Nasdaq IPO late Thursday. The move marks a pivotal moment for the biotech and the gene editing field. The novel CRISPR enzyme developer was created nine ...
    Endpoints · 24d ago↗ source
  • STAT+: Medicare takes another swing at 340B cuts to hospitals
    Reducing Medicare payments for 340B drugs is the latest proposal focused on the hotly debated drug discount program.
    STAT · 24d ago↗ source
  • STAT+: Lawmakers urge HHS to force Eli Lilly to provide 340B drug discounts to hospitals
    Lawmakers step into a dispute between Eli Lilly and hospitals about the 340b drug discount program.
    STAT · 24d ago↗ source
  • STAT+: Elevance sues government over $115 million tied to Medicare Advantage star ratings
    The health insurer says CMS didn't calculate its star ratings appropriately.
    STAT · 24d ago↗ source