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  • AstraZeneca receives FDA approval for new hypertension medication
    AstraZeneca announced that the U.S. Food and Drug Administration has approved its hypertension drug, marking a regulatory milestone for the company. The approval adds to AstraZeneca's cardiovascul…
    STAT · 3mo agoApprovalPositive↗ source
  • Merck and Kelun-Biotech's ADC sac-TMT secures first global Phase 3 win ahead of schedule
    Merck and China-based Kelun-Biotech reported that their experimental antibody-drug conjugate sac-TMT achieved a positive outcome in a global Phase 3 study, marking the first such success for the ca…
    Endpoints · 3mo agoPositive readoutPositive↗ source
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  • Maryland board caps Ozempic price at $274 per month, aiming to save $5.8 million annually
    Maryland's Prescription Drug Affordability Board announced a price ceiling for Ozempic, a type 2 diabetes medication. The cap limits the cost of a 30‑day supply to $274, a figure based on Medicare…
    STAT · 3mo agoRegulatoryPositive↗ source
  • White House expands TrumpRx, adding 600 generics through Amazon, GoodRx and Cost Plus partnership
    The White House announced an expansion of its prescription drug discount platform, TrumpRx, adding more than 600 generic medicines to the site. The new catalog is supplied through partnerships wit…
    STAT · 3mo agoRegulatoryPositive↗ source
  • CMS moves to allow lower-premium, less comprehensive ACA exchange plans starting 2027
    The Centers for Medicare and Medicaid Services finalized a proposal that will let Affordable Care Act exchange plans offer more limited coverage and lower monthly premiums beginning in 2027. The r…
    STAT · 3mo agoRegulatoryNegative↗ source
  • Republican lawmaker releases FDA analysis of alleged pediatric Covid vaccine deaths
    A Republican congressman has made public an analysis that the FDA commissioned to examine claims of child deaths linked to Covid-19 vaccines. The study was initiated by former senior FDA officials…
    Endpoints · 3mo agoRegulatoryNeutral↗ source
  • WakeMed and Atrium Health finalize two-year secret merger, sparking local backlash and national attention
    Hospital executives from WakeMed and Atrium Health worked on a merger in secrecy for two years before announcing the deal. The combination brings together two major health systems in North Carolina…
    STAT · 3mo agoDealNeutral↗ source
  • U.S. imposes 30-day entry ban on travelers from Ebola-affected DRC, Uganda, South Sudan
    The CDC issued an order banning non-citizen travelers who have been in the Democratic Republic of the Congo, Uganda, or South Sudan within the past 21 days from entering the United States. The ban…
    STAT · 3mo agoRegulatoryNeutral↗ source
  • Regeneron signs up to $125 million deal with Parabilis to target difficult drug targets
    Regeneron announced a deal with Parabilis Medicines valued up to $2.2 billion, with an upfront payment of $125 million. The agreement aims to give Regeneron access to Parabilis’s platform that dis…
    Endpoints · 3mo agoDealNeutral↗ source
  • Supreme Court Declines to Hear Lawsuits Against Medicare Drug Price Negotiation Program
    The U.S. Supreme Court on Monday refused to hear challenges to the Medicare drug price negotiation program, delivering a setback to the pharmaceutical industry's legal effort. The Court declined t…
    STAT · 3mo agoRegulatoryNegative↗ source
  • US biotech faces internal split over reliance on Chinese-developed drug candidates
    Ed Silverman's Pharmalittle column notes that US biotech firms are wrestling with how to treat Chinese partners, with some seeing them as collaborators and others as competitors. The column highli…
    STAT · 3mo agoNegative↗ source
  • Regeneron's LAG-3 inhibitor fianlimab fails Phase 3 skin cancer trial
    Regeneron announced that its experimental LAG-3 inhibitor fianlimab did not meet its primary endpoint in a late-stage trial for a skin cancer indication. The Phase 3 study was designed to evaluate…
    Endpoints · 3mo agoNegative readoutNegative↗ source
  • Pharma firms turn to outsourcing to boost value of aging drug portfolios
    For many years pharma companies treated legacy brands as low-maintenance cash generators, focusing only on steady but declining revenue once patents expired. With the largest patent cliff in histo…
    BioPharma Dive · 3mo agoPositive↗ source
  • Experts debate testing Merck’s Ervebo vaccine for DRC Ebola outbreak amid lack of approved shot
    The Democratic Republic of the Congo confirmed a new Ebola outbreak at the end of May, making it the fourth largest on record. The virus is spreading in a conflict-affected region, complicating con…
    STAT · 3mo agoNegative↗ source
  • Design Therapeutics reports early Friedreich's ataxia trial shows 6.4-point improvement; Vincentage reports Chinese obesity data
    Design Therapeutics disclosed Phase 1/2 results for its Friedreich's ataxia candidate DT-216P2. The trial administered a 1 mg/kg dose and reported an average 6.4-point improvement on the study endp…
    Endpoints · 3mo agoPositive readoutPositive↗ source
  • Supreme Court declines to hear pharma challenges to Medicare drug price negotiations
    The U.S. Supreme Court has refused to review several lawsuits filed by drug makers contesting the Medicare drug price negotiation provisions of the Inflation Reduction Act. The cases, brought by co…
    Endpoints · 3mo agoRegulatoryNeutral↗ source
  • Trump administration cuts childhood vaccine schedule, citing personal autonomy
    The opinion argues that the concept of patient autonomy does not apply to childhood vaccination because infants cannot refuse shots; the decision rests with parents. In January, the Department of…
    STAT · 3mo agoRegulatoryNegative↗ source
  • Goodman urges five reforms to restore trust in CDC vaccine advisory committee
    Jesse Goodman, a former director of the FDA's Center for Biologics Evaluation and Research and former chief scientist, wrote an opinion piece calling for major changes to the CDC's Advisory Committ…
    STAT · 3mo agoRegulatoryNegative↗ source
  • Regeneron immunotherapy combo comes up short in melanoma trial
    A two-drug regimen of Regeneron’s fianlimab and Libtayo didn’t significantly outperform Keytruda in a late-stage study, a finding that surprised Wall Street analysts and wiped out billions in marke…
    BioPharma Dive · 3mo agoRegulatoryNeutral↗ source
  • Texas launches clinic to support individuals seeking detransition services
    Texas health officials announced the opening of a clinic dedicated to people who want to reverse a gender transition, marking a new service in the state. The facility will provide counseling, medi…
    STAT · 3mo agoNeutral↗ source
  • WHO declares Ebola outbreak in DRC an international public health emergency
    The World Health Organization announced on Saturday that the Ebola outbreak first identified in the Democratic Republic of the Congo has been declared an international public health emergency. The…
    STAT · 3mo agoNegative↗ source
  • UK advocacy groups threaten legal action over pharma trade deal provision on medicine cost-effectiveness
    Two UK advocacy groups are demanding that the government reverse regulations embedded in a newly finalised pharma trade agreement with the United States. They argue the provision could let external…
    STAT · 3mo agoRegulatoryNegative↗ source
  • Americans in Congo May Have Been Exposed to Ebola; One Shows Possible Symptoms, Tests Pending
    Several Americans traveling in the Democratic Republic of the Congo are believed to have had high risk exposure to suspected Ebola cases, according to sources familiar with the situation. At least…
    STAT · 3mo agoNeutral↗ source
  • Conflicting guidelines leave women unsure when to start routine mammograms
    Deciding when to begin routine mammograms is confusing because major health groups recommend different starting ages-some say 40, others 45, and a recent recommendation pushes the start to 50. They…
    STAT · 3mo agoNeutral↗ source
  • Senator Bill Cassidy loses Louisiana primary, paving way for Trump-backed Julia Letlow
    Senator Bill Cassidy, a leading Republican on health issues, finished third in Louisiana’s Senate primary with about 24.8% of the vote. State treasurer John Fleming received roughly 28%, while Rep.…
    STAT · 3mo agoNeutral↗ source