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BioSpace·Jul 29·1 min read
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Caldera and Vidya secure $478M via reverse mergers to go public

Jul 29, 2026·read at BioSpace ↗DealPositive

Caldera Therapeutics, a U.S. bispecific antibody biotech, announced a reverse merger with Nasdaq-listed Synlogic to become a public company.

The deal includes a $278 million private placement from investors such as Bain Capital Life Sciences, TCGX, Atlas Venture, venBio Partners and Blackstone Multi‑Asset Investing, giving them 34.9% of the combined entity while Caldera’s existing backers retain 62.8%.

Vidya Therapeutics completed a separate reverse merger, and together the two companies raised $478 million to advance immunology and inflammation programs.

These transactions highlight that reverse mergers remain a viable path for venture‑backed biotechs to access public markets after setbacks like Synlogic’s failed Phase 3 trial.

source

This writeup was produced by pharmadog from original reporting by BioSpace.

Original headline: “Private biotechs Caldera and Vidya raise $478M collectively in reverse go-public mergers”

read at BioSpace ↗
562 words · retrieved Jul 29
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companies & drugs in this story

companies
PATH3Processa Pharmaceuticals, Inc.Ultragenyx Pharmaceutical Inc.
drugs
Immunology3
topics
Immunology4Bispecific Antibody3IBD (Crohn's + UC)3Monoclonal Antibody3Endocrinology & MetabolismMultiple SclerosisRare DiseaseSmall Molecule

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