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STAT·May 5·1 min read
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Cytokinetics’ Myqorzo hits twin efficacy targets in genetic heart disease trial, while Viridian reports positive Phase 3 data for elegrobart

May 5, 2026·read at STAT ↗Positive readoutPositive

Cytokinetics announced that its experimental heart‑failure drug Myqorzo achieved both primary efficacy endpoints in a study of patients with genetic cardiomyopathy, showing significant symptom improvement.

The trial’s results were highlighted as meeting the study’s twin efficacy goals, suggesting the drug could address an unmet need in this patient population.

In related biotech news, Viridian Therapeutics disclosed positive top‑line results from a Phase 3 trial of elegrobart in chronic thyroid eye disease, indicating a favorable benefit‑risk profile.

Meanwhile, Vertex Pharmaceuticals reported first‑quarter earnings in line with expectations but said it is halting development of the mRNA cystic fibrosis candidate VX‑522 after tolerability concerns, and Pfizer and Alkermes also posted earnings.

Analysts are urged to scrutinize these developments closely, especially given ongoing discussions about other companies’ safety data.

source

This writeup was produced by pharmadog from original reporting by STAT.

Original headline: “STAT+: Are analysts too quick to gloss over Lilly’s liver case?”

read at STAT ↗
491 words · retrieved May 5
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companies & drugs in this story

companies
CYTOKINETICS6JOHNSON & JOHNSON3LILLY2Moderna, Inc.2PFIZER2Viridian Therapeutics Inc2AXSOME
drugs
MYQORZO6aficamten6elegrobart2
topics
Cardiology6IBD (Crohn's + UC)3Cystic Fibrosis2Hepatology2Ophthalmology2mRNA Therapeutic2Heart FailureImmunologyMonoclonal Antibody

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