drug · small molecule

REZENOPY

updated 3mo ago

by $SCNX Scienture Holdings, Inc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 4 investigational indications.

targets

Opioid receptors; mu/kappa/delta

all catalysts(0)

nothing on the calendar yet

Trials studying REZENOPY

phase2A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockadenot yet recruitingn=16
phase1Pharmacodynamic Evaluation of Intranasal Nalmefenecompletedn=84
phase4A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Strokecompletedn=446
phase4Clinical Outcomes From Nalmefenewithdrawn

News(5)

Narcan maker Emergent BioSolutions eliminates top R&D role in sweeping restructuring
Two and a half years into his tenure as Emergent BioSolutions CEO, Joseph Papa is executing another round of restructuring to align the business with “current business realities.”
fiercebiotech · 8d ago
Syphilis spreads while researchers contend with federal constraints and a drug shortage
At the San Diego-Tijuana border, syphilis spreads while researchers contend with federal constraints and a drug shortage.
stat · 14d ago
Trump administration will bring special ed to HHS
Infant mortality rate dips, OTC naloxone options rise, and other health news from Morning Rounds
stat · 1mo ago
FDA Broadens Access to Over-the-Counter Naloxone Nasal Spray for Opioid Overdose
The U.S. Food and Drug Administration (FDA) today approved another over-the-counter (OTC) intranasal naloxone product, Rextovy, a 4 milligram (mg) naloxone hydrochloride nasal spray for the emergen…
fda_press · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago

brand

REZENOPY

trade names

Evzio, Evzio (autoinjector), Kloxxado, Naloxone hydrochloride, Naloxone hydrochloride (autoinjector), Naloxone hydrochloride component of bunavail

generic

NALOXONE HYDROCHLORIDE

MOA

12.1 Mechanism of Action Naloxone hydrochloride is an opioid antagonist that antagonizes opioid effects by competing for the same receptor sites. Naloxone hydrochloride reverses the effects of opioids, including respiratory depression, sedation, and hypotension. It can also reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine.

indication

1 INDICATIONS AND USAGE REZENOPY nasal spray is indicated for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression in adult and pediatric patients. REZENOPY nasal spray is intended for immediate administration as emergency therapy in settings where opioids may be present. REZENOPY nasal spray is not a substitute for emergency medical care. REZENOPY nasal spray is an opioid antagonist for the emergency treatment of known or suspected opioid overdose, as manifested by respiratory and/or central nervous system depression in adult and pediatric patients. ( 1 ) REZENOPY nasal spray is intended for immediate administration as emergency therapy in settings where opioids may be present. ( 1 ) REZENOPY nasal spray is not a substitute for emergency medical care. ( 1 )

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 50m ago

Found something off?

comments(0)

5-min edit window · permanent after that

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drug · small molecule

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REZENOPY

updated 3mo ago

by $SCNX Scienture Holdings, Inc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 4 investigational indications.

targets

Opioid receptors; mu/kappa/delta

all catalysts(0)

nothing on the calendar yet

Trials studying REZENOPY

phase2A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockadenot yet recruitingn=16
phase1Pharmacodynamic Evaluation of Intranasal Nalmefenecompletedn=84
phase4A Phase 4 Clinical Study to Investigate the Efficacy and Safety of Naloxone HCI IV in Patients With Strokecompletedn=446
phase4Clinical Outcomes From Nalmefenewithdrawn

News(5)

Narcan maker Emergent BioSolutions eliminates top R&D role in sweeping restructuring
Two and a half years into his tenure as Emergent BioSolutions CEO, Joseph Papa is executing another round of restructuring to align the business with “current business realities.”
fiercebiotech · 8d ago
Syphilis spreads while researchers contend with federal constraints and a drug shortage
At the San Diego-Tijuana border, syphilis spreads while researchers contend with federal constraints and a drug shortage.
stat · 14d ago
Trump administration will bring special ed to HHS
Infant mortality rate dips, OTC naloxone options rise, and other health news from Morning Rounds
stat · 1mo ago
FDA Broadens Access to Over-the-Counter Naloxone Nasal Spray for Opioid Overdose
The U.S. Food and Drug Administration (FDA) today approved another over-the-counter (OTC) intranasal naloxone product, Rextovy, a 4 milligram (mg) naloxone hydrochloride nasal spray for the emergen…
fda_press · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago

brand

REZENOPY

trade names

Evzio, Evzio (autoinjector), Kloxxado, Naloxone hydrochloride, Naloxone hydrochloride (autoinjector), Naloxone hydrochloride component of bunavail

generic

NALOXONE HYDROCHLORIDE

MOA

indication

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 50m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

REZENOPY

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying REZENOPY

News(5)

Report a data issue

comments(0)

REZENOPY

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying REZENOPY

News(5)

Report a data issue

comments(0)