drug · small molecule

SUBLOCADE

updated 3mo ago

by $INDV Indivior Pharmaceuticals, Inc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 23 investigational indications.

targets

Kappa-type opioid receptorMu-type opioid receptor

all catalysts(0)

nothing on the calendar yet

Trials studying SUBLOCADE

phase2A Study of Brenipatide in Participants With Opioid Use Disorderrecruitingn=465
phase1Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadonerecruitingn=32
—Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infantsrecruitingn=1,600
phase4Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.recruitingn=600
phase4Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile Pharmacy Clinicnot yet recruitingn=60
—Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancyrecruitingn=100
—Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-studycompletedn=71
phase2INDV-6001 Multiple-Dose Pharmacokinetic Studycompletedn=123

more trials →

News(6)

Trump administration’s new ‘treatment first’ addiction toolkit emphasizes faith, abstinence
The White House nods to use of addiction medications but moves away from other harm reduction strategies.
stat · 1d ago
Supernus and Indivior merge to create CNS mega-company with 11 approved drugs
Supernus Pharmaceuticals and Indivior Pharmaceuticals are outlining a combined expected $2.2 billion in annual revenue, plus $125 million in cost savings that will include “natural redundancies.”
biospace · 11d ago
Supernus, Indivior merge to beef up brain drug portfolio
The transaction combines two companies marketing nearly a dozen neurological drugs that bring in steady, but not blockbuster sales for conditions such as opioid use disorder and Parkinson's.
biopharma_dive · 11d ago
12 ideas for tackling the U.S. alcohol epidemic
The U.S. can save lives from excess alcohol use without taking drastic measures. Here are 12 steps that can help.
stat · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago
Trump administration warns against using federal dollars on fentanyl test strips
The Trump administration underlines a “clear shift away from harm reduction and practices” that it says facilitates illegal drug use.
stat · 3mo ago

brand

SUBLOCADE

trade names

Brixadi, Bupeaze, Buplast, Butec, Butrans, Buvidal

generic

BUPRENORPHINE

MOA

12.1 Mechanism of Action SUBLOCADE Injection contains buprenorphine. Buprenorphine is a partial agonist at the mu- opioid receptor and an antagonist at the kappa-opioid receptor.

indication

1 INDICATIONS AND USAGE SUBLOCADE is indicated for the treatment of moderate to severe opioid use disorder in patients who have initiated treatment with a single dose of a transmucosal buprenorphine product or who are already being treated with buprenorphine. SUBLOCADE should be used as part of a complete treatment plan that includes counseling and psychosocial support. SUBLOCADE contains buprenorphine, a partial opioid agonist, and is indicated for the treatment of moderate to severe opioid use disorder in patients who have initiated treatment with a single dose of a transmucosal buprenorphine product or who are already being treated with buprenorphine. ( 1 ) SUBLOCADE should be used as part of a complete treatment program that includes counseling and psychosocial support. ( 1 )

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 48m ago

Found something off?

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5-min edit window · permanent after that

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drug · small molecule

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SUBLOCADE

updated 3mo ago

by $INDV Indivior Pharmaceuticals, Inc.🔗 ChEMBL

community read0 votes

🐶 often sniffed alongside

top 8

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 23 investigational indications.

targets

Kappa-type opioid receptorMu-type opioid receptor

all catalysts(0)

nothing on the calendar yet

Trials studying SUBLOCADE

phase2A Study of Brenipatide in Participants With Opioid Use Disorderrecruitingn=465
phase1Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadonerecruitingn=32
—Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infantsrecruitingn=1,600
phase4Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.recruitingn=600
phase4Acceptability and Feasibility of Extended-Release Subcutaneous Buprenorphine on a Mobile Pharmacy Clinicnot yet recruitingn=60
—Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancyrecruitingn=100
—Medication Treatment for Opioid Use Disorder in Expectant Mothers: Infant Neurodevelopmental Outcomes Sub-studycompletedn=71
phase2INDV-6001 Multiple-Dose Pharmacokinetic Studycompletedn=123

more trials →

News(6)

Trump administration’s new ‘treatment first’ addiction toolkit emphasizes faith, abstinence
The White House nods to use of addiction medications but moves away from other harm reduction strategies.
stat · 1d ago
Supernus and Indivior merge to create CNS mega-company with 11 approved drugs
Supernus Pharmaceuticals and Indivior Pharmaceuticals are outlining a combined expected $2.2 billion in annual revenue, plus $125 million in cost savings that will include “natural redundancies.”
biospace · 11d ago
Supernus, Indivior merge to beef up brain drug portfolio
The transaction combines two companies marketing nearly a dozen neurological drugs that bring in steady, but not blockbuster sales for conditions such as opioid use disorder and Parkinson's.
biopharma_dive · 11d ago
12 ideas for tackling the U.S. alcohol epidemic
The U.S. can save lives from excess alcohol use without taking drastic measures. Here are 12 steps that can help.
stat · 1mo ago
Are Republicans turning against medications for treating opioid addiction?
Federal actions and proposals have reignited debate over methadone and buprenorphine, worrying addiction experts and patient groups.
stat · 2mo ago
Trump administration warns against using federal dollars on fentanyl test strips
The Trump administration underlines a “clear shift away from harm reduction and practices” that it says facilitates illegal drug use.
stat · 3mo ago

brand

SUBLOCADE

trade names

Brixadi, Bupeaze, Buplast, Butec, Butrans, Buvidal

generic

BUPRENORPHINE

MOA

12.1 Mechanism of Action SUBLOCADE Injection contains buprenorphine. Buprenorphine is a partial agonist at the mu- opioid receptor and an antagonist at the kappa-opioid receptor.

indication

Data sources

ClinicalTrials.gov · OpenTargets

last refreshed 48m ago

Found something off?

comments(0)

5-min edit window · permanent after that

no comments yet — first sniff?

SUBLOCADE

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying SUBLOCADE

News(6)

Report a data issue

comments(0)

SUBLOCADE

🐶 often sniffed alongside

targets

all catalysts(0)

Trials studying SUBLOCADE

News(6)

Report a data issue

comments(0)