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  2. ›drugs
  3. ›SUBOXONE
drug · small molecule
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SUBOXONE

updated 3mo ago
by $INDV Indivior Pharmaceuticals, Inc.🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval1,644 co-mentions · 528 sources
  • drugBUPRENORPHINE HYDROCHLORIDE AND NALOXONE HYDROCHLORIDE1,330 co-mentions · 528 sources
  • drugbuprenorphine ER1,276 co-mentions · 528 sources
  • drugBUTRANS1,276 co-mentions · 528 sources
  • drugBRIXADI1,276 co-mentions · 528 sources
  • drugbuprenorphine1,276 co-mentions · 528 sources
  • drugBUPRENORPHINE HYDROCHLORIDE1,276 co-mentions · 528 sources
  • drugSUBLOCADE1,276 co-mentions · 528 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for opioid dependence and drug dependence and 1 investigational indication.

targets

Kappa-type opioid receptorMu-type opioid receptor

all catalysts(0)

nothing on the calendar yet

Trials studying SUBOXONE

  • phase2INDV-6001 Multiple-Dose Pharmacokinetic Studycompletedn=123
  • phase1Study to Assess Repeated Doses of INDV-2000 in Healthy Volunteers and in Treatment Seeking Individuals With Opioid Use Disordercompletedn=64

News(2)

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    stat · 2mo ago
brand
SUBOXONE
trade names
Belbuca, Buprenex, Buprenorphine hydrochloride, Buprenorphine hydrochloride component of bunavail, Buprenorphine hydrochloride component of cassipa, Buprenorphine hydrochloride component of suboxone
generic
BUPRENORPHINE HYDROCHLORIDE
MOA
12.1 Mechanism of Action SUBOXONE sublingual film contains buprenorphine and naloxone. Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. Naloxone is a potent antagonist at mu opioid receptors and produces opioid withdrawal signs and symptoms in individuals physically dependent on full opioid agonists when administered parenterally.
indication
1 INDICATIONS AND USAGE SUBOXONE sublingual film is indicated for treatment of opioid dependence. SUBOXONE sublingual film should be used as part of a complete treatment plan that includes counseling and psychosocial support. SUBOXONE® sublingual film contains buprenorphine, a partial‐opioid agonist, and naloxone, an opioid antagonist, and is indicated for treatment of opioid dependence. ( 1 ) SUBOXONE sublingual film should be used as part of a complete treatment plan that includes counseling and psychosocial support. ( 1 )
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 18m ago
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