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  • Rocket Pharmaceuticals sells pediatric disease priority review voucher for $180 million; Oruka eyes $500 million offering
    Rocket Pharmaceuticals, a New Jersey gene-therapy company, sold its priority review voucher for a rare pediatric disease to an undisclosed buyer for $180 million. The voucher was earned after the…
    Endpoints · 4mo agoDealNeutral↗ source
  • Devoted Health reports first revenue decline in 2025 amid Medicare Advantage turbulence
    Devoted Health, a startup offering Medicare Advantage plans, saw its revenue and membership drop in 2025, marking the first decline since it began offering plans seven years ago. The downturn refl…
    Endpoints · 4mo agoNegative↗ source
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  • Adaptyv Bio shares results from its latest AI-driven protein design contest
    Adaptyv Bio, a biotech firm focused on protein engineering, released the outcomes of its newest competition that tests how well artificial‑intelligence models can create novel proteins. The challe…
    Endpoints · 4mo agoNeutral↗ source
  • Intellia's in-body CRISPR therapy achieves first Phase 3 success
    Intellia announced that its experimental in vivo CRISPR gene‑editing therapy has completed a Phase 3 trial with positive results. This is the first instance of a CRISPR‑based treatment delivered d…
    Endpoints · 4mo agoPositive readoutPositive↗ source
  • Sun Pharma to acquire Organon for $11.75 billion in all-cash deal
    Indian pharmaceutical company Sun Pharma announced it will purchase Organon, a company focused on women's health and biosimilars that was spun out of Merck in 2021. The transaction is an all-cash…
    Endpoints · 4mo agoDealPositive↗ source
  • Intellia reports positive Phase 3 readout for CRISPR gene-editing therapy in hereditary angioedema
    Intellia Therapeutics announced that its CRISPR-based therapy achieved a successful readout in a Phase 3 trial for hereditary angioedema, a rare condition marked by sudden, potentially dangerous sw…
    Endpoints · 4mo agoPositive readoutPositive↗ source
  • Eli Lilly to pay up to $2.3B for Ajax's JAK inhibitor in cancer deal
    Eli Lilly announced a new agreement with Ajax Therapeutics to acquire rights to a JAK inhibitor called Kyle LaHucik for cancer treatment. The transaction could be worth up to $2.3 billion, reflect…
    Endpoints · 4mo agoDealPositive↗ source
  • Compass Therapeutics reports secondary endpoint data from pivotal biliary tract cancer trial, shares stock drop
    Compass Therapeutics announced new secondary‑endpoint results from its pivotal bispecific antibody trial in second‑line biliary tract cancer, a year after reporting a Phase 2/3 success. The additi…
    Endpoints · 4mo agoNegative readoutNegative↗ source
  • Erasca releases early-stage RAS drug data amid legal dispute with Revolution Medicines
    Erasca has released early-stage data on its RAS-targeting compound, doing so after receiving a legal threat from rival Revolution Medicines. Revolution recently announced a new drug that revived h…
    Endpoints · 4mo agoNeutral↗ source
  • Thermo Fisher to divest microbiology unit to Astorg for $1.075 billion; Ligand announces purchase of XOMA
    Thermo Fisher Scientific announced it will sell its microbiology business, part of its specialty diagnostics segment, to European private‑equity firm Astorg. The transaction is valued at $1.075 bi…
    Endpoints · 4mo agoDealNeutral↗ source
  • Oruka Therapeutics reports Phase 2 psoriasis results with 63% of patients showing plaque improvement
    Oruka Therapeutics announced results from its Phase 2 trial in moderate to severe plaque psoriasis. The study enrolled 63 patients and 40 of them, about 63.5%, achieved the predefined level of ski…
    Endpoints · 4mo agoPositive readoutPositive↗ source
  • AI-driven biotech Fathom Therapeutics secures $47 million Series A funding and rebrands from Atommap
    Fathom Therapeutics, the company formerly known as Atommap, announced that it has closed a $47 million Series A financing round. The capital raise will support the firm’s effort to combine artifici…
    Endpoints · 4mo agoDealPositive↗ source
  • Veradermics reports positive Phase 2/3 results for oral Rogaine in men with pattern hair loss
    Veradermics, a biotech that recently went public, announced that its oral formulation of Rogaine met the primary endpoints in a late-stage Phase 2/3 trial. The study enrolled men with mild-to-mode…
    Endpoints · 4mo agoPositive readoutPositive↗ source
  • Revolution Medicines threatens lawsuit against Erasca over RAS drug patent and efficacy claims
    Earlier this month a newly announced cancer therapy generated strong interest from patients and investors. The drug, which targets the RAS pathway, was highlighted for its potential impact on oncol…
    Endpoints · 4mo agoRegulatoryNegative↗ source
  • Utah doctors urge state to suspend Doctronic AI prescription-refill program
    Utah medical licensing board members have asked the state to halt a temporary program that lets startup Doctronic use artificial intelligence to refill prescriptions. The board says the AI-driven…
    Endpoints · 4mo agoRegulatoryNegative↗ source
  • UK biotech funding shows early recovery after mid-2025 lull, BIA reports
    The BioIndustry Association released data indicating that equity financing for UK biotech companies is beginning to rise again in early 2026. The trend follows a slowdown that began in mid-2025, w…
    Endpoints · 4mo agoPositive↗ source
  • Endpoints Weekly celebrates Neal Awards while previewing Sanofi, Lilly and RevMed updates
    Endpoints Weekly released its latest edition on April 25, 2026, noting a celebratory tone after the publication earned three Neal Awards for B2B journalism excellence. The issue highlights several…
    Endpoints · 4mo agoPositive↗ source
  • Sanofi’s tolebrutinib receives EU CHMP endorsement for specific multiple sclerosis patients despite US FDA setback
    Sanofi's BTK inhibitor tolebrutinib is moving toward approval in the European Union for a subset of multiple sclerosis patients. The Committee for Medicinal Products for Human Use (CHMP) of the Eu…
    Endpoints · 4mo agoRegulatoryPositive↗ source
  • Avalyn Pharma targets $182M IPO as WHO prequalifies Novartis malaria drug
    Avalyn Pharma announced plans for an initial public offering that could raise about $182 million in net proceeds. The company is developing inhaled formulations of drugs already approved for pulmon…
    Endpoints · 4mo agoDealNeutral↗ source
  • Novartis withdraws EU filing for Pluvicto label expansion into early-stage prostate cancer
    Novartis announced it has pulled its application to the European Medicines Agency to extend the label of its radioligand therapy Pluvicto for use in earlier stages of prostate cancer. The move com…
    Endpoints · 4mo agoRegulatoryNegative↗ source
  • FDA grants fast-track vouchers to three psychedelic firms
    The FDA announced it has issued fast-track development vouchers to three companies working on psychedelic therapies. The recipients are R&DCompass, Transcend, and the Usona Institute. The vouchers…
    Endpoints · 4mo agoRegulatoryPositive↗ source
  • UC Berkeley spinout explores gene-editing approach to GLP-1 based weight-loss therapy
    UC Berkeley researchers have launched a startup that plans to use jumping genes to deliver GLP-1 gene therapy for obesity treatment. The approach seeks to create a long-lasting source of the hormon…
    Endpoints · 4mo agoNeutral↗ source
  • Daiichi Sankyo delays release of annual results, shares fall
    Daiichi Sankyo announced it will postpone the reporting of its annual results, saying more time is needed to finalize the numbers. The company had planned to unveil the financials for its fiscal y…
    Endpoints · 4mo agoNegative↗ source
  • Pfizer strategy chief Andrew Baum departs, stays on as senior advisor; Helus Pharma appoints new CEO after two months
    Andrew Baum, formerly chief strategy and innovation officer at Pfizer, has left that role. He will continue to work with the company as a senior strategic advisor to CEO Albert Bourla. Meanwhile,…
    Endpoints · 4mo agoNeutral↗ source
  • Regeneron secures first FDA approval for gene therapy treating rare inherited hearing loss
    Regeneron announced that the U.S. Food and Drug Administration has approved its gene-based treatment Otarmeni, marking the first approval of a therapy for inherited hearing loss. The therapy is de…
    Endpoints · 4mo agoApprovalPositive↗ source