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BioSpace·1h ago·1 min read
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Takeda and Protagonist Therapeutics receive FDA approval for rusfertide (Mimrylo) to treat polycythemia vera

Aug 31, 2026·read at BioSpace ↗ApprovalPositive

The FDA approved rusfertide, to be sold as Mimrylo, for the treatment of polycythemia vera, a rare blood cancer, marking a key win for Takeda and its partner Protagonist Therapeutics.

The decision relied on data from the Phase 3 VERIFY study, which showed that adding Mimrylo to standard care helped keep hematocrit levels below the 45% threshold that reduces clot risk.

Jefferies analysts estimate the drug could generate up to $2 billion in peak sales, adding to Takeda’s growth pipeline after a recent approval of its narcolepsy medicine Orzeyful.

The two approvals are described as the first major launches in Takeda’s next growth cycle, signaling momentum for the company’s upcoming product launches.

source

This writeup was produced by pharmadog from original reporting by BioSpace.

Original headline: “Takeda, Protagonist score broad FDA nod in rare blood cancer, setting up $2B opportunity”

read at BioSpace ↗
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companies & drugs in this story

companies
Ultragenyx Pharmaceutical Inc.5Vera Therapeutics, Inc.5CYCLE2BRISTOLBRISTOL MYERS SQUIBBBRISTOL MYERS SQUIBB CODisc Medicine, Inc.
drugs
zasocitinib2deucravacitinibiron
topics
Hematology9Rare Disease5Approval4Oncology4Dermatology2Peptide TherapeuticPsoriasis

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