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  1. pharmadog
  2. ›drugs
  3. ›SANDIMMUNE
drug · protein
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SANDIMMUNE

updated 3mo ago
/ /ˌsaɪkləˈspɔrɪn/ /
by $NVS NOVARTIS AG🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 6
  • tagApproval492 co-mentions · 124 sources
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  • tagSmall Molecule172 co-mentions · 86 sources
  • tagRecall1 co-mentions · 1 sources

Protein drug with a maximum clinical stage of Approval (across all indications), with 12 approved and 71 investigational indications.

targets

Peptidyl-prolyl cis-trans isomerase A

all catalysts(0)

nothing on the calendar yet

Trials studying SANDIMMUNE

  • phase4Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunctionrecruitingn=48
  • phase4Comparison of Conjunctival Goblet Cell Density in Dry Eye Patients Treated With Cyclosporine 0.1% Dissolved in Perfluorobutylpentane (Vevye®) or Generic 0.05% Cyclosporine Emulsion for 8 Weeksnot yet recruitingn=60
  • —Real-World Assessment of VEVYE® for Short-Term Symptom and Sign Improvement of Dry Eye Disease in a Neuro-Ophthalmology Clinic: A 6-Month Prospective Observational Studyrecruitingn=50
  • phase3Extension Trial on Efficacy / Safety of L-CsA + SoC in Treating BOS in Post Single or Double Lung Transplant (BOSTON-3)terminatedn=164
  • phase2Ruxolitinib Based GVHD Prophylaxis Regimen Before, During, and After Hematopoietic Cell Transplantation in Older Adult Patients With Acquired Aplastic Anemiarecruitingn=20
  • phase2Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignanciesrecruitingn=60
  • phase3Efficacy + Safety of Liposome Cyclosporine A to Treat Bronchiolitis Obliterans Post Double Lung Transplant (BOSTON-2)completedn=169
  • phase3A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medicationsrecruitingn=102
more trials →

News(1)

  • With $263M, LifeMine unearths a new drug for organ transplants
    Led by serial biotech entrepreneur Greg Verdine, the startup mined fungi genomes to find a safer alternative to the drugs widely used to prevent the body from rejecting transplanted organs.
    biopharma_dive · 8d ago
brand
SANDIMMUNE
trade names
Capimune, Capsorin, Cequa, Cyclosporine, Deximune, Gengraf
generic
CYCLOSPORINE
MOA
Cyclophilin A modulator
indication
INDICATIONS AND USAGE Sandimmune capsules and Sandimmune injection, in combination with adrenal corticosteroids, are indicated for the: Prophylaxis of organ rejection in kidney, liver, and heart allogeneic transplants. Treatment of chronic rejection in patients previously treated with other immunosuppressive agents. Because of the risk of anaphylaxis, Sandimmune injection should be reserved for patients who are unable to take the Sandimmune capsules.
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 9m ago
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