drug · antibody
lecanemab
Marketedupdated 3mo agoby Eisai Co Ltd🔗 ChEMBL
Approvedannual revenue · 2024–2024peak $231M
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🐶 often sniffed alongside
top 2Antibody drug with a maximum clinical stage of Approval (across all indications), with an approval for 3 indications.
indications
investigational
Alzheimer's Disease
targets
Amyloid-beta precursor protein
all catalysts(8)
approval · 8
Jan 6, 2023
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Jul 6, 2023
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Nov 14, 2024
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Jan 24, 2025
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Aug 21, 2025
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Dec 15, 2025
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Dec 15, 2025
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Jan 16, 2026
approval
LEQEMBI (LECANEMAB-IRMB) — FDA approval
lecanemab
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Trials studying lecanemab
- phase3A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease
- phase3AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid
- phase3DIAN-TU Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease
- phase2A Study to Evaluate Safety, Tolerability, and Efficacy of Lecanemab in Subjects With Early Alzheimer's Disease
- phase3Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol DIAN-TU-001
- phase3Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU)
- phase2A Study of E2814 With Concurrent Lecanemab Treatment in Participants With Early Alzheimer's Disease
- EP1Safety and Feasibility of Exablate Blood-Brain Barrier Disruption for Mild Cognitive Impairment or Mild Alzheimer's Disease Undergoing Standard of Care Monoclonal Antibody (mAb) Therapy
News(10)
- Biogen validated the Alzheimer’s tau theory. CEO Viehbacher still isn’t betting the storeWith so many unknowns, Biogen is carefully eyeing its next-gen Alzheimer’s treatment diranersen as a high-risk, high-reward project with the potential for a major payout around 2030.biospace · 13d ago
- Earnings roundup: Biogen’s ‘resiliency,’ AstraZeneca’s growth pitch and GSK’s oncology pushBetter-than-expected sales helped Biogen regain the support of investors, while AstraZeneca and GSK worked to convince Wall Street that they can hit ambitious revenue targets.biopharma_dive · 13d ago
- Leqembi records best quarter since launch as Biogen raises underlying guidanceLeqembi, the anti-amyloid Alzheimer’s drug from Eisai and Biogen, recorded $184 million in global sales in the second quarter, Biogen said Wednesday morning. It's the best showing for Leqembi since…endpoints · 13d ago
- Biogen counts on drugs from Apellis deal to patch Leqembi's slow salesIt’s no secret that sales of Leqembi have been disappointing. First approved in 2023, the Alzheimer’s drug from Eisai and Biogen launched shortly after Chris Viehbacher took the reins as Biogen CEO…endpoints · 19d ago
- Erasca's $550M offering; Summit sells an antibioticPlus, news about subcutaneous Leqembi, WuXi AppTec and Q32 Bio. 📊 Erasca targets $550M for KRAS drugs: The biotech's public offering came after it shared a small ...endpoints · 28d ago
- STAT+: Akero team, backed by Fairmount, launches new immunology companyFDA approves injectable Leqembi, another post-Makary reversal, and other biotech news from The Readoutstat · 28d ago
- Biogen data highlight promise, questions surrounding tau-targeting Alzheimer’s drugsThe study provides the clearest evidence yet that medicines like BIIB080 might improve cognition, but leaves unclear why higher doses didn’t perform better.biopharma_dive · 28d ago
- STAT+: Medicare’s miss on Alzheimer’s drug spendingFar fewer seniors than expected are taking costly Alzheimer's drugs.stat · 3mo ago
- STAT+: Pharmalittle: We’re reading about Medicare and Alzheimer’s drugs, estrogen patch shortages, and morePeople on Medicare are not getting the recently approved Alzheimer’s medications nearly as much as federal officials anticipatedstat · 3mo ago
- STAT+: Medicare is spending far less than expected on new Alzheimer’s drugsAdoption has been slow with new Alzheimer’s drugs because the treatments are complicated to administer and the benefits are uncertain.stat · 3mo ago
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