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  1. pharmadog
  2. ›drugs
  3. ›cabozantinib
drug · small molecule
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cabozantinib

pre_registrationupdated 5mo ago
by Lotus Pharmaceutical Co Ltd🔗 ChEMBL
community read0 votes

🐶 often sniffed alongside

top 5
  • tagApproval48 co-mentions · 24 sources
  • drugCABOMETYX48 co-mentions · 24 sources
  • drugCOMETRIQ48 co-mentions · 24 sources
  • drugcabozantinib s-malate48 co-mentions · 24 sources
  • tagSmall Molecule24 co-mentions · 24 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 4 approved and 41 investigational indications.

targets

Hepatocyte growth factor receptorVascular endothelial growth factor receptor 2

all catalysts(0)

nothing on the calendar yet

Trials studying cabozantinib

  • phase2A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Other Agents in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)recruitingn=474
  • phase3Extension Study for Participants in Studies That Include Belzutifan (MK-6482-043/LITESPARK-043)recruitingn=450
  • phase2Cabozantinib in High Grade Neuroendocrine Neoplasmsactive not recruitingn=35
  • phase2Study of Cabozantinib and Nivolumab in Metastatic Castration Resistant Prostate Canceractive not recruitingn=47
  • phase3Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinomarecruitingn=720
  • phase3Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Studyenrolling by invitationn=5,000
  • phase1Dose-Escalation Study of Cabozantinib in Combination With Lutetium-177 (177Lu)-PSMA-617 in Patients With Metastatic Castration-Resistant Prostate Cancerrecruitingn=33
  • phase1Modulation of the Bone Immune Microenvironment Following Cabozantinib Treatment of Bone Metastatic Clear Cell Renal Cell Carcinoma: Proof of Concept Studyrecruitingn=16

News(2)

  • Did Exelixis use a 'trivial' modification to its cash cow to product-hop past a patent cliff? These researchers think so
    When Exelixis CEO Michael Morrissey rolled out the biotech's final numbers for 2025 earlier in the year, there was no mistaking the outsized role that cabozantinib played in funding the company and…
    endpoints · 1mo ago
  • GU Cancer Experts Highlight Top Abstracts to Watch During ASCO 2026
    We spoke with leading voices in GU oncology to see which presentations they are most looking forward to during the 2026 ASCO Annual Meeting.
    onclive · 4mo ago
generic
cabozantinib
MOA
Hepatocyte growth factor receptor inhibitor; Vascular endothelial growth factor receptor 2 inhibitor
indication
Hepatocellular Carcinoma
phase
pre_registration
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 3h ago
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