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  1. pharmadog
  2. ›drugs
  3. ›bupropion
drug · small molecule
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bupropion

Phase 2updated 3mo ago
by Bioron Pharma🔗 ChEMBL
Phase 2
community read0 votes

🐶 often sniffed alongside

top 8
  • tagApproval824 co-mentions · 412 sources
  • drugAUVELITY551 co-mentions · 399 sources
  • drugWELLBUTRIN541 co-mentions · 399 sources
  • drugWELLBUTRIN SR459 co-mentions · 399 sources
  • tagSmall Molecule412 co-mentions · 412 sources
  • drugBUPROPION HYDROCHLORIDE399 co-mentions · 399 sources
  • drugbupropion hydrochloride ER399 co-mentions · 399 sources
  • drugbupropion hydrochloride MR399 co-mentions · 399 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 3 approved and 23 investigational indications.

targets

Sodium-dependent dopamine transporterSodium-dependent noradrenaline transporter

all catalysts(0)

nothing on the calendar yet

Trials studying bupropion

  • phase3A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapyactive not recruitingn=420
  • phase1A Phase 1, First-in-human Study of VX-433recruitingn=118
  • —Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infantsrecruitingn=1,600
  • phase4A Randomized Controlled Trial Comparing the Effectiveness of Different Treatment Options for Weight Management After Discontinuation of Semaglutide and Tirzepatide (GLP1 Transition Trial)completedn=226
  • phase2Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorderrecruitingn=30
  • phase4Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE)active not recruitingn=8,600
  • phase1A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participantscompletedn=22
  • phase1Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participantscompletedn=30
more trials →

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    stat · 3mo ago
generic
bupropion
MOA
Dopamine transporter inhibitor; Norepinephrine transporter inhibitor
indication
Type 1 Narcolepsy (Narcolepsy with Cataplexy)
phase
phase_2
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 35m ago
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