clinical trial · NCT07223671
Study to Evaluate the Effect of Repotrectinib on the Drug Levels of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants
Bristol-Myers Squibb·phase1·completed·n = 30
Healthy VolunteersRepotrectinibMetforminDigoxinRosuvastatinBupropionFlurbiprofenOmeprazole
brief summary
The purpose of the study if to evaluate the effect of Repotrectinib on the drug levels of transporter and CYP P450 probe substrates in healthy adult participants.
started
Dec 31, 2025
primary completion
Feb 19, 2026
completion
Mar 19, 2026
last updated
Mar 27, 2026
official title
Phase 1, 2-Cohort, Open-label, Fixed-sequence, Drug-drug Interaction Study to Evaluate the Effect of Repotrectinib on the Pharmacokinetics of Transporter and CYP P450 Probe Substrates in Healthy Adult Participants
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol