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  1. pharmadog
  2. ›drugs
  3. ›Sublocade
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save

buprenorphine LA

Marketedupdated 3mo ago
by $INDV Indivior Pharmaceuticals, Inc.
Approved
community read0 votes

🐶 often sniffed alongside

top 6
  • tagApproval40 co-mentions · 20 sources
  • drugSUBLOCADE40 co-mentions · 20 sources
  • drugbuprenorphine ER20 co-mentions · 20 sources
  • drugbuprenorphine20 co-mentions · 20 sources
  • drugBRIXADI20 co-mentions · 20 sources
  • drugBUTRANS20 co-mentions · 20 sources

Small molecule drug with a maximum clinical stage of Approval (across all indications), with 7 approved and 23 investigational indications.

all catalysts(25)

approval · 25
Nov 30, 2017
approval
$INDV39.01+2.07%
9y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Mar 5, 2018
approval
$INDV39.01+2.07%
8y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Oct 7, 2019
approval
$INDV39.01+2.07%
7y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Feb 4, 2020
approval
$INDV39.01+2.07%
7y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Jun 15, 2020
approval
$INDV39.01+2.07%
6y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Mar 4, 2021
approval
$INDV39.01+2.07%
5y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
May 11, 2021
approval
$INDV39.01+2.07%
5y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Jun 17, 2021
approval
$INDV39.01+2.07%
5y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Sep 22, 2021
approval
$INDV39.01+2.07%
5y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Jun 17, 2022
approval
$INDV39.01+2.07%
4y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Aug 23, 2022
approval
$INDV39.01+2.07%
4y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Jan 6, 2023
approval
$INDV39.01+2.07%
4y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Mar 13, 2023
approval
$INDV39.01+2.07%
3y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
May 23, 2023
approval
3y ago
BRIXADI (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Jul 3, 2023
approval
$INDV39.01+2.07%
3y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Sep 12, 2023
approval
$INDV39.01+2.07%
3y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Dec 15, 2023
approval
3y ago
BRIXADI (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Dec 15, 2023
approval
$INDV39.01+2.07%
3y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Apr 19, 2024
approval
$INDV39.01+2.07%
2y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Feb 21, 2025
approval
$INDV39.01+2.07%
1y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Mar 28, 2025
approval
1y ago
BRIXADI (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Apr 11, 2025
approval
$INDV39.01+2.07%
1y ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Aug 29, 2025
approval
12mo ago
BRIXADI (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Dec 22, 2025
approval
$INDV39.01+2.07%
8mo ago
SUBLOCADE (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
Dec 22, 2025
approval
8mo ago
BRIXADI (BUPRENORPHINE) — FDA approval
buprenorphine LA
→
view all 25 catalysts →

Trials studying buprenorphine LA

  • phase2INDV-6001 Multiple-Dose Pharmacokinetic Studycompletedn=123
  • phase4SUBLOCADE Rapid Initiation Extension Studycompletedn=17
  • phase4SUBLOCADE Rapid Initiation Studycompletedn=26

Patent cliff

source: FDA Orange Book
first barrier falls
Jan 10, 2027
148 days

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (79)

  • Jun 22, 2038method-of-use (U-2489)US 10646484
  • Nov 6, 2035method-of-use (U-3111)US 11000520
  • Nov 6, 2035method-of-use (U-3111)US 11000520
  • Nov 6, 2035method-of-use (U-3111)US 11839611
  • Nov 6, 2035method-of-use (U-3111)US 11839611
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032method-of-use (U-3617)US 10912772
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11110084
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 11135215
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12161640
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 12318379
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jul 26, 2032formulationUS 9937164
  • Jan 6, 2032formulationUS 8921387
  • Jan 6, 2032formulationUS 8921387
  • Sep 5, 2031formulationUS 8975270
  • Sep 5, 2031formulationUS 8975270
  • Jun 25, 2031formulationUS 105583944.9y
  • Jun 25, 2031formulationUS 105583944.9y
  • Jun 6, 2031method-of-use (U-2489)US 101982184.8y
  • Jun 6, 2031method-of-use (U-2489)US 101982184.8y
  • Jun 6, 2031method-of-use (U-2489)US 105921684.8y
  • Jun 6, 2031method-of-use (U-2489)US 105921684.8y
  • Jun 6, 2031method-of-use (U-2177)US 92720444.8y
  • Jun 6, 2031method-of-use (U-2177)US 92720444.8y
  • Jun 6, 2031formulationUS 94984324.8y
  • Jun 6, 2031formulationUS 94984324.8y
  • Jun 6, 2031formulationUS 97824024.8y
  • Jun 6, 2031formulationUS 97824024.8y
  • Jun 6, 2031formulationUS 98272414.8y
  • Jun 6, 2031formulationUS 98272414.8y
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jan 10, 2027formulationUS 8236292148d
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755
  • Jul 31, 2026formulationUS 8236755

FDA exclusivities (9)

  • Feb 21, 2028M-314Method (3y)1.5y
  • Feb 21, 2028M-314Method (3y)1.5y
  • May 23, 2026NPNP
  • May 23, 2026NPNP
  • May 23, 2026NPNP
  • May 23, 2026NPNP
  • May 23, 2026NPNP
  • May 23, 2026NPNP
  • May 23, 2026NPNP

News(2)

  • Supernus and Indivior merge to create CNS mega-company with 11 approved drugs
    Supernus Pharmaceuticals and Indivior Pharmaceuticals are outlining a combined expected $2.2 billion in annual revenue, plus $125 million in cost savings that will include “natural redundancies.”
    biospace · 11d ago
  • Supernus, Indivior merge to beef up brain drug portfolio
    The transaction combines two companies marketing nearly a dozen neurological drugs that bring in steady, but not blockbuster sales for conditions such as opioid use disorder and Parkinson's.
    biopharma_dive · 11d ago
brand
Sublocade
generic
buprenorphine [INN]
MOA
12.1 Mechanism of Action SUBLOCADE Injection contains buprenorphine. Buprenorphine is a partial agonist at the mu- opioid receptor and an antagonist at the kappa-opioid receptor.
indication
Opium (Opioid) Addiction
phase
marketed
Data sources
openFDA · ClinicalTrials.gov
last refreshed 16m ago
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