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  1. pharmadog
  2. ›drugs
  3. ›Bupivacaine Hydrochloride
drug · small molecule
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bupivacaine hydrochloride

Marketedupdated 3mo ago
by OncoZenge AB🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

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Small molecule drug with a maximum clinical stage of Approval (across all indications), with an approval for pain and 25 investigational indications.

targets

Sodium channel protein type 4 subunit alpha

all catalysts(0)

nothing on the calendar yet

Trials studying bupivacaine hydrochloride

  • phase2A Study of Bupivacaine Liposome Injection in the Treatment of Pain After Thoracoscopic Surgeryrecruitingn=96
  • phase3Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Painenrolling by invitationn=150
  • phase2Study Assessing Pain Relief After Replacement of the Kneecompletedn=226
  • phase2Study Assessing Pain Relief After Replacement of the Kneeterminatedn=112
  • —Impact of Opioid Avoidance Protocol for ACL Reconstructioncompletedn=32
  • phase2Sustained Release Lidocaine for the Treatment of Postoperative Painrecruitingn=120
  • phase3Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplastycompletedn=167
  • phase4Comparison of Clorotekal and Bupivacaine for Short Obstetric Surgerysuspendedn=27
more trials →

Patent cliff

source: FDA Orange Book
first barrier falls
May 20, 2029
~2.8 years out

Earliest of all listed patents + FDA exclusivities. Generic / biosimilar entry typically only becomes possible AFTER both patent and exclusivity barriers expire.

patents (2)

  • Jan 9, 2033formulationUS 11746141
  • May 20, 2029method-of-use (U-2949)US RE478262.8y

News(2)

  • Convenience Kit Correction: Medline Issues Correction for Kits Containing Huons Lidocaine Hydrochloride and Bupivacaine Hydrochloride in Dextrose Injection
    Medline is correcting affected convenience kits by removing recalled Lidocaine Hydrochloride and Bupivacaine Hydrochloride in Dextrose Injection components from affected convenience kits.
    fda_medwatch · 8d ago
  • Convenience Kit Recall: B. Braun Medical, Inc. Removes Spinal Anesthesia Kits Containing Huons Bupivacaine Hydrochloride in Dextrose Injection, USP
    B. Braun is removing affected convenience kits containing recalled Bupivacaine Hydrochloride in Dextrose Injection components
    fda_medwatch · 26d ago
brand
Bupivacaine Hydrochloride
trade names
Bupivac hcl, Bupivacaine hydrochloride, Bupivacaine hydrochloride component of duocaine, Bupivacaine hydrochloride component of sensorcaine, Bupivacaine hydrochloride kit, Bupivacaine hydrochloride preservative free
generic
bupivacaine hydrochloride
MOA
Sodium channel protein type IV alpha subunit blocker
indication
Oral Mucositis
phase
marketed
Data sources
ClinicalTrials.gov · OpenTargets
last refreshed 49m ago
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