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  1. pharmadog
  2. ›drugs
  3. ›Ahzantive
drug · protein
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aflibercept biosimilar

Marketedupdated 5mo ago
by Sam Chun Dang Pharm Co Ltd🔗 ChEMBL
Approved
community read0 votes

🐶 often sniffed alongside

top 7
  • tagApproval20 co-mentions · 10 sources
  • drugEYLEA HD17 co-mentions · 10 sources
  • drugEylea15 co-mentions · 10 sources
  • drugYESAFILI9 co-mentions · 7 sources
  • drugENZEEVU6 co-mentions · 3 sources
  • companySandoz Inc3 co-mentions · 3 sources
  • companyBiocon Biologics Ltd2 co-mentions · 2 sources

Protein drug with a maximum clinical stage of Approval (across all indications), with 16 approved and 39 investigational indications.

indications

investigational
Diabetic Macular Edema

targets

Placenta growth factorVascular endothelial growth factor A, long form

all catalysts(3)

approval · 3
Aug 9, 2024
approval
2y ago
ENZEEVU (AFLIBERCEPT-ABZV) — FDA approval
aflibercept biosimilar
→
Feb 10, 2025
approval
2y ago
ENZEEVU (AFLIBERCEPT-ABZV) — FDA approval
aflibercept biosimilar
→
Feb 12, 2026
approval
8mo ago
ENZEEVU (AFLIBERCEPT-ABZV) — FDA approval
aflibercept biosimilar
→

Trials studying aflibercept biosimilar

  • phase3Efficacy and Safety of the Aflibercept FYB203 Biosimilar in Comparison to Eylea® in Patients With Neovascular Age-Related Macular Degenerationcompletedn=434
  • phase3Clinical Study to Compare Efficacy and Safety of AVT06 and EU-Eylea (ALVOEYE)completedn=413
  • phase3A Study to Compare SB15 (Proposed Aflibercept Biosimilar) to Eylea in Subjects With Neovascular Age-related Macular Degeneration (AMD)completedn=449

News(10)

  • This week in charts: Kodiak’s big comeback and Hengrui’s dealmaking
    The latest installment in BioPharma Dive’s data visualization series features a closer look at Kodiak’s stock performance and Hengrui's ties with U.S. and European drugmakers.
    biopharma_dive · 1d ago
  • Lilly, Foghorn part ways; Wave’s FDA-approved plans
    The pharma giant cut its partnership after a cancer drug disappointed in testing. Elsewhere, Teva and Samsung Bioepis expanded a partnership and space biotech Varda brought in $251 million.
    biopharma_dive · 2d ago
  • Kodiak skyrockets on positive study data for 2 eye drugs
    The Phase 3 findings suggested Kodiak might have multiple threats to Regeneron’s Eylea and added more than $3 billion to the company’s market value.
    biopharma_dive · 5d ago
  • Kodiak's stock soars as it clinches crucial Phase 3 win for Eylea competitor
    Kodiak Sciences appears to have an Eylea successor on its hands. The Silicon Valley biotech said its experimental drug Zenkuda performed as well as Eylea in a progressive eye disease known as wet a…
    endpoints · 5d ago
  • Kodiak Sciences’ stock soars 166% after 2 assets match Eylea in Phase 3 trial
    Kodiak Sciences will head to regulators with one of the candidates, an anti-VEGF antibody called zenkuda, after the late-stage results.
    biospace · 5d ago
  • STAT+: AbbVie wins FDA nod for Parkinson’s pill
    The FDA has approved AbbVie’s once-daily Parkinson’s pill for sales, based on a late-stage study that showed the drug helped improve symptoms.
    stat · 5d ago
  • Kodiak's stock doubles as resurrected eye disease drug matches Eylea in phase 3
    Two of Kodiak Sciences’ drug candidates have matched aflibercept in a phase 3 clinical trial, positioning the biotech to seek FDA approval of one of the eye disease assets this year.
    fiercebiotech · 5d ago
  • Merck sees pivotal victory for $3B eye disease prospect
    Merck & Co.’s Brunello trial has hit its primary endpoint, shedding light on the effects of a trispecific diabetic macular edema (DME) drug candidate that the Big Pharma bought in a $3 billion take…
    fiercebiotech · 9d ago
  • Regeneron to challenge Ipsen as FDA clears bone disease drug
    Pasatru’s approval sets up a market battle in a rare indication where the only available treatment has generated disappointing sales.
    biopharma_dive · 1mo ago
  • EyePoint’s bid to compete with Eylea falls flat
    EyePoint’s experimental eye treatment came up short of Eylea, the current go-to option for wet age-related macular degeneration, according to results of a Phase 3 trial. The company’s shares {$EYPT…
    endpoints · 1mo ago
view all news mentions →
brand
Ahzantive
trade names
Eylea, Yesafili, Zaltrap
generic
aflibercept-abzv
MOA
Placenta growth factor inhibitor; Vascular endothelial growth factor A inhibitor
indication
Diabetic Macular Edema
phase
marketed
Data sources
openFDA · ClinicalTrials.gov · OpenTargets
last refreshed 1h ago
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