clinical trial · NCT07797478
A Study of RO7890597 in Healthy Adult Volunteers
Genentech, Inc.·phase1·recruiting·n = 139
Healthy VolunteersRO7890597PlaceboRabeprazoleItraconazole
brief summary
This study will evaluate the safety, pharmacokinetics (PK), and activity of single and multiple doses of RO7890597 compared with placebo in healthy volunteers. The study includes single ascending dose (SAD) stage, multiple ascending dose (MAD) stage, food-effect and proton pump inhibitor (PPI) stages, and a supplemental drug-drug interaction (DDI) stage.
started
Aug 28, 2026
primary completion
Jun 8, 2027
completion
Jun 8, 2027
last updated
Sep 1, 2026
official title
A Phase I Study to Evaluate the Safety and Pharmacokinetics of RO7890597 Following Single and Multiple Ascending Doses, and the Effects of Food, Proton-Pump Inhibition, And CYP3A Inhibition in Healthy Adult Volunteers
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol