clinical trial · NCT07548606
A Drug-Drug Interaction Study of Itraconazole and Opevesostat (MK-5684) in Healthy Adult Male Participants (MK-5684-017)
Merck Sharp & Dohme LLC·phase1·active not recruiting·n = 14
HealthyOpevesostatPrednisoneFludrocortisone acetateItraconazole
brief summary
Researchers have designed a study medicine called opevesostat as a new way to treat prostate cancer. The purpose of this study is to learn what happens to opevesostat in a person's body over time (a pharmacokinetic or PK study). Researchers will compare what happens to opevesostat in the body when it is given with and without another medicine called itraconazole.
started
May 11, 2026
primary completion
Jun 1, 2026
completion
Jun 14, 2026
last updated
Jun 12, 2026
official title
A Phase 1, Open-Label, Fixed-Sequence Study to Evaluate the Effects of Multiple Doses of Itraconazole on the Single-Dose Pharmacokinetics of MK-5684 in Healthy Adult Male Participants
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol