clinical trial · NCT07535463
A Study of Ivonescimab, Chemotherapy, and Stereotactic Radiosurgery for People With Non-Small Cell Lung Cancer
Non-Small Cell Lung CancerIvonescimabStereotactic Radiosurgery
brief summary
The researchers are doing this study to test the safety of ivonescimab given in combination with standard chemotherapy and stereotactic radiosurgery (SRS) in people with non-small cell lung cancer (NSCLC) that has spread to the brain (brain metastases). The researchers will test different doses of the study drug to find the best dose that causes few or mild side effects in participants. Once the dose is found, the researchers will test it in a new group of participants to see if it is effective in treating their NSCLC brain metastases.
started
Apr 10, 2026
primary completion
Apr 1, 2028
completion
Apr 1, 2028
last updated
Apr 17, 2026
official title
Safety and Efficacy of Ivonescimab and Chemotherapy Plus Stereotactic Radiosurgery (SRS) in the Treatment of Non-Small Cell Lung Cancer Brain Metastases
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol