clinical trial · NCT07517445
Bactericidal Activity and Safety of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Drug-susceptible Pulmonary Tuberculosis
Gates Medical Research Institute·phase2·recruiting·n = 165
Drug Susceptible Pulmonary TuberculosisBedaquiline, pretomanid, linezolidBedaquiline, pretomanid, linezolidBedaquiline, pretomanid, linezolidNicotinamide (NAM)
brief summary
The purpose of this study is to determine if nicotinamide in combination with bedaquiline, pretomanid, and linezolid, is safe and effective in treating drug-susceptible pulmonary tuberculosis.
started
Apr 13, 2026
primary completion
Jun 14, 2027
completion
Jun 14, 2027
last updated
Apr 22, 2026
official title
A Phase 2, Open-label, Randomized Controlled Trial to Assess the Safety, Bactericidal Activity, and Pharmacokinetics of Nicotinamide in Combination With Bedaquiline, Pretomanid, and Linezolid in Adults With Drug-susceptible Pulmonary Tuberculosis
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol