A Study on the Novel Oncolytic Virus Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma
brief summary
A single-arm clinical study on the efficacy and safety of the novel oncolytic virus Ad-TD-nsIL12 combined with PD-1 inhibitors in the treatment of recurrent high-grade glioma
detailed description
This study is a single-arm, single-center, exploratory clinical trial evaluating the preliminary efficacy and safety of the oncolytic virus Ad-TD-nsIL12 in combination with a PD-1 inhibitor for the treatment of recurrent HGG. It is planned to enroll 12-15 HGG patients and use a treatment regimen of Ad-TD-nsIL12 combined with a PD-1 inhibitor to preliminarily assess the efficacy and safety of this regimen.
official title
A Single-arm Clinical Study on the Efficacy and Safety of the Novel Oncolytic Virus Ad-TD-nsIL12 Combined With PD-1 Inhibitor in the Treatment of Recurrent High-grade Glioma