clinical trial · NCT07420257
A Randomized, Double-blind, Placebo-controlled Phase III Study to Evaluate the Efficacy and Safety of CM326 in Participants With Chronic Rhinosinusitis With Nasal Polyposis
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.·phase3·not yet recruiting·n = 212
Chronic Rhinosinusitis With Nasal PolypsCM326 injectionPlacebo of CM326
brief summary
This is a multi-center, randomized, double blind, placebo-controlled Phase III study to evaluate the efficacy and safety of CM326, and to observe the Pharmacokinetics, Pharmacodynamics and I immumogenicity\[c2.1\] of CM326 in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).The study consists of four periods, including an up to 4-week screening/run-in period, a 24-week double-blind randomized treatment period, a 28-week open-label treatment period, and an 8-week safety follow-up period.
started
Feb 28, 2026
primary completion
Oct 30, 2028
completion
Oct 30, 2028
last updated
Feb 19, 2026
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol