clinical trial · NCT07354984
A Single-Arm Phase II Clinical Study of Docetaxel Combined With Nimotuzumab and Pucotenlimab as Second-Line and Beyond Therapy for Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
Sun Yat-sen University·phase2·not yet recruiting·n = 30
Recurrent/Metastatic Head and Neck Squamous Cell CarcinomaDrug Combination Therapy
brief summary
This study is a single-arm Phase II trial designed to evaluate the efficacy and safety of Docetaxel, Nimotuzumab, and Pucotenlimab combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma who have failed prior PD-1/PD-L1 inhibitor and platinum-based therapies, for second-line and later-line treatment.
started
Jan 1, 2026
primary completion
Dec 31, 2029
completion
Dec 31, 2029
last updated
Jan 21, 2026
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol