clinical trial · NCT07025824
Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation
Technische Universität Dresden·phase2·not yet recruiting·n = 220
AML - Acute Myeloid LeukemiaMDS (Myelodysplastic Syndrome)Treosulfan (Treo)Melphalan (Mel)Fludarabine (Flud)
brief summary
The aim of this study is to compare the effectiveness and tolerability of two conditioning chemotherapies prior to allogeneic stem cell transplantation. The following will also be investigated: * Survival * Remission and Relapse rate * Engraftment or graft failure * Graft versus Host Disease (GvHD)
started
Sep 1, 2025
primary completion
Dec 1, 2028
completion
Dec 1, 2028
last updated
Sep 3, 2025
official title
Randomized Evaluation of Treosulfan Versus Melphalan Conditioning Followed by PTCy in Patients With AML and MDS Undergoing Allogeneic Transplantation
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol