clinical trial · NCT06995287
Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Severe Primary Dysmenorrhea
Nantes University Hospital·phase3·recruiting·n = 222
Primary DysmenorrheaChronic Pelvic PainXeominPlacebo
brief summary
The objective of the study is to evaluate the global impression of improvement at 3 months following intramyometrial botulinum toxin injections via hysteroscopy in women with severe primary dysmenorrhea who have failed first-line medical treatment, compared to intramyometrial placebo injections.
started
Feb 9, 2026
primary completion
Jun 9, 2028
completion
Sep 9, 2028
last updated
Feb 12, 2026
detailed description
This trial is multicenter, placebo-controlled, randomized with center-based stratification, double-blind and prospective. The treatment consists of a single injection follow by 6 months of follow-up.
official title
Evaluation of the Analgesic Effect of Intramyometrial Botulinum Toxin Injection Via Hysteroscopy in Severe Primary Dysmenorrhea: a Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Study
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol