clinical trial · NCT06989775
BoxX-NoAF Clinical Trial
AtriCure, Inc.·N/A·recruiting·n = 960
Post Operative Atrial FibrillationAtrial Fibrillation, PostoperativeIsolator® Synergy™ EnCompass® Ablation System and AtriClip® LAA Exclusion System
brief summary
Post Operative Atrial Fibrillation (POAF) is the most common complication of cardiac surgery. POAF incidence can exceed 50% depending on the patient baseline characteristics and surgery type. Patients with POAF tend to have worse acute and long-term clinical outcomes. BoxX-NoAF is a randomized trial to evaluate if prophylactic ablation and exclusion of the Left Atrial Appendage at the time of other routine cardiac surgery can reduce the incidence of post operative AF and clinical AF during long term follow up in patients who have not yet developed AF but are at risk.
started
Oct 24, 2025
primary completion
Nov 1, 2028
completion
Nov 1, 2031
last updated
Apr 7, 2026
official title
EnCompass Clamp and the AtriClip in Box Lesion and Left Atrial Appendage EXclusion Procedure for the Prevention of New Onset of Atrial Fibrillation
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol