clinical trial · NCT06952868
Boron Neutron Capture Therapy With B10 L-BPA for Unresectable Recurrent Head and Neck Cancers
China Medical University Hospital·phase2·recruiting·n = 24
Head and Neck CancerBoron Neutron Capture TherapyDrug: B10 L-BPA Injection
brief summary
This Phase II study, titled "A Phase II Study to Evaluate the Efficacy and Safety of Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Patients with Unresectable Recurrent Head and Neck Cancers," aims to assess the efficacy and safety of B10 L-BPA-based BNCT in this patient population. The primary objective is to evaluate its efficacy, while secondary objectives include assessing safety, survival outcomes, tumor response, and the pharmacokinetics (PK) profile of B10 L-BPA and boron.
started
May 23, 2025
primary completion
Aug 31, 2026
completion
Feb 28, 2027
last updated
Aug 28, 2026
official title
A Phase II Study to Evaluate the Efficacy and Safety of the Boron Neutron Capture Therapy (BNCT) Using the B10 L-BPA as Boron Carrier in Patients With Unresectable Recurrent Head and Neck Cancers
sourced from ClinicalTrials.gov · pharmadog mirrors structured fields, not the full protocol